G2Cdb::Gene report

Gene id
G00002011
Gene symbol
MYH11 (HGNC)
Species
Homo sapiens
Description
myosin, heavy chain 11, smooth muscle
Orthologue
G00000762 (Mus musculus)

Databases (9)

Curated Gene
OTTHUMG00000073427 (Vega human gene)
Gene
ENSG00000133392 (Ensembl human gene)
4629 (Entrez Gene)
168 (G2Cdb plasticity & disease)
MYH11 (GeneCards)
Literature
160745 (OMIM)
Marker Symbol
HGNC:7569 (HGNC)
Protein Expression
2302 (human protein atlas)
Protein Sequence
P35749 (UniProt)

Synonyms (2)

  • SMHC
  • SMMHC

Diseases (9)

Disease Nervous effect Mutations Found Literature Mutations Type Genetic association?
D00000093: Acute myeloid leukaemia N Y (15041229) Translocation fusion (with another gene) (TF) N
D00000093: Acute myeloid leukaemia N Y (15075086) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15167911) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15223639) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15224374) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15269306) Translocation fusion (with another gene) (TF) Y
D00000090: Precursor-B-cell acute lymphoblastic leukaemia N Y (15339697) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15339697) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (15820957) Deletion (D) Y
D00000103: Leukaemia N Y (15968309) Translocation fusion (with another gene) (TF) Y
D00000118: Therapy-related myelodysplastic syndrome N Y (16165210) Translocation fusion (with another gene) (TF) Y
D00000095: Chronic myelogenous leukaemia N Y (16203287) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (16281071) Translocation fusion (with another gene) (TF) Y
D00000095: Chronic myelogenous leukaemia N Y (16393682) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (16393682) Translocation fusion (with another gene) (TF) Y
D00000239: Ascending thoracic aortic aneurysms leading to type A dissections N Y (16444274) Splice site mutation (SpS) Y
D00000239: Ascending thoracic aortic aneurysms leading to type A dissections N Y (16444274) Microinsertion (MI) Y
D00000287: Patent ductus arteriosus N Y (16444274) Splice site mutation (SpS) Y
D00000287: Patent ductus arteriosus N Y (16444274) Microinsertion (MI) Y
D00000093: Acute myeloid leukaemia N Y (16504290) Translocation fusion (with another gene) (TF) Y
D00000097: Granulocytic sarcoma of mesentery N Y (16504290) Translocation fusion (with another gene) (TF) Y
D00000288: Infantile hypertrophic pyloric stenosis N Y (16826529) No mutation found (N) N
D00000093: Acute myeloid leukaemia N Y (17052753) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (17287858) Translocation fusion (with another gene) (TF) Y

References

Literature (49)

Pubmed - human_disease

Pubmed - other

Gene lists (7)

Gene List Source Species Name Description Gene count
L00000009 G2C Homo sapiens Human PSD Human orthologues of mouse PSD adapted from Collins et al (2006) 1080
L00000015 G2C Homo sapiens Human NRC Human orthologues of mouse NRC adapted from Collins et al (2006) 186
L00000016 G2C Homo sapiens Human PSP Human orthologues of mouse PSP adapted from Collins et al (2006) 1121
L00000059 G2C Homo sapiens BAYES-COLLINS-HUMAN-PSD-CONSENSUS Human cortex PSD consensus 748
L00000061 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-CONSENSUS Mouse cortex PSD consensus (ortho) 984
L00000069 G2C Homo sapiens BAYES-COLLINS-HUMAN-PSD-FULL Human cortex biopsy PSD full list 1461
L00000071 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-FULL Mouse cortex PSD full list (ortho) 1556
© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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