G2C::Project

G2C uses genome information as part of a general strategy for understanding cognition at the molecular, cellular and systems neuroscience levels. We use a multi-disciplinary approach to psychiatric diseases including learning impairment, cognitive decline with ageing, dementias, schizophrenia and related psychoses, and brain injury.

We aim to:

• understand normal cognitive function at a new level of detail;
• find the basis of neurodegenerative diseases;
• generate valuable genetic resources for animal and human research;
• create, and make publicly available, novel databases for basic and clinical neuroscience; and
• establish a general model for tackling diseases and brain function.

Our integrative approach should help to bring together the disciplines of psychiatric genetics (which has yet to identify genes for major psychiatric disorders) and animal behavioural psychology (which does not yet exploit the great strides made in understanding human cognitive psychology).

G2C in Depth: An Integrative Neuroscience Program Linking Mouse Genes to Cognition and Disease

Follow these links for a detailed description of the G2C programme and its organization.

• Introduction
• General Strategy & Outline
  
• Connecting the Molecular Mechanisms of Learning
  
• A Multilayer Organisation
  • Layer 1: Identification of Genes Encoding Assemblies
  • Layer 2: Genomics
  • Layer 3: Functional Genomics - Experimental Neuroscience
  • Layer 4: Informatics
• Structural Issues for a Large Multidisciplinary Program
• Conclusions