G2Cdb::Gene report
- Gene id
- G00002531
- Gene symbol
- SNAP25 (HGNC)
- Species
- Homo sapiens
- Description
- synaptosomal-associated protein, 25kDa
- Orthologue
- G00001282 (Mus musculus)
Databases (9)
- Curated Gene
- OTTHUMG00000031863 (Vega human gene)
- Gene
- ENSG00000132639 (Ensembl human gene)
- 6616 (Entrez Gene)
- 99 (G2Cdb plasticity & disease)
- SNAP25 (GeneCards)
- Literature
- 600322 (OMIM)
- Marker Symbol
- HGNC:11132 (HGNC)
- Protein Expression
- 360 (human protein atlas)
- Protein Sequence
- P60880 (UniProt)
Synonyms (6)
- RIC-4
- RIC4
- SEC9
- SNAP-25
- bA416N4.2
- dJ1068F16.2
Diseases (9)
| Disease | Nervous effect | Mutations Found | Literature | Mutations Type | Genetic association? |
|---|---|---|---|---|---|
| D00000166: Schizophrenia | Y | Y | (11287790) | Repeat polymorphism (RP) | Y |
| D00000291: Alagille syndrome | N | Y | (9205123) | Deletion (D) | ? |
| D00000179: Attention deficit hyperactivity disorder | Y | Y | (17325713) | Single nucleotide polymorphism (SNP) | ? |
| D00000179: Attention deficit hyperactivity disorder | Y | Y | (16088329) | Polymorphism (P) | ? |
| D00000166: Schizophrenia | Y | Y | (15823421) | Polymorphism (P) | Y |
| D00000153: Obesity | N | Y | (15823421) | Polymorphism (P) | N |
| D00000179: Attention deficit hyperactivity disorder | Y | Y | (15007392) | Single nucleotide polymorphism (SNP) | Y |
| D00000179: Attention deficit hyperactivity disorder | Y | Y | (15007392) | Microsatellite polymorphism (MSP) | Y |
| D00000248: Netherton syndrome | N | Y | (16670861) | Deletion (D) | Y |
| D00000140: Diabetes mellitus Type 1 | N | Y | (16519819) | Single nucleotide polymorphism (SNP) | N |
| D00000248: Netherton syndrome | N | Y | (16225619) | Microinsertion (MI) | Y |
| D00000248: Netherton syndrome | N | Y | (16120162) | Single nucleotide polymorphism (SNP) | Y |
| D00000247: Atopic dermatitis | N | Y | (15949016) | Polymorphism (P) | N |
| D00000248: Netherton syndrome | N | Y | (15942217) | Insertion (I) | Y |
| D00000247: Atopic dermatitis | N | Y | (15753919) | Polymorphism (P) | Y |
| D00000315: Food allergy | N | Y | (15753919) | Polymorphism (P) | Y |
| D00000240: Asthma | N | Y | (15753894) | Single nucleotide polymorphism (SNP) | N |
| D00000247: Atopic dermatitis | N | Y | (15753894) | Single nucleotide polymorphism (SNP) | N |
| D00000248: Netherton syndrome | N | Y | (15656819) | Single nucleotide polymorphism (SNP) | Y |
References
Literature (132)
Pubmed - human_disease
Pubmed - other
Gene lists (10)
| Gene List | Source | Species | Name | Description | Gene count |
|---|---|---|---|---|---|
| L00000009 | G2C | Homo sapiens | Human PSD | Human orthologues of mouse PSD adapted from Collins et al (2006) | 1080 |
| L00000011 | G2C | Homo sapiens | Human clathrin | Human orthologues of mouse clathrin coated vesicle genes adapted from Collins et al (2006) | 150 |
| L00000012 | G2C | Homo sapiens | Human Synaptosome | Human orthologues of mouse synaptosome adapted from Collins et al (2006) | 152 |
| L00000015 | G2C | Homo sapiens | Human NRC | Human orthologues of mouse NRC adapted from Collins et al (2006) | 186 |
| L00000016 | G2C | Homo sapiens | Human PSP | Human orthologues of mouse PSP adapted from Collins et al (2006) | 1121 |
| L00000039 | G2C | Homo sapiens | Pocklington H8 | Human orthologues of cluster 8 (mouse) from Pocklington et al (2006) | 3 |
| L00000059 | G2C | Homo sapiens | BAYES-COLLINS-HUMAN-PSD-CONSENSUS | Human cortex PSD consensus | 748 |
| L00000061 | G2C | Homo sapiens | BAYES-COLLINS-MOUSE-PSD-CONSENSUS | Mouse cortex PSD consensus (ortho) | 984 |
| L00000069 | G2C | Homo sapiens | BAYES-COLLINS-HUMAN-PSD-FULL | Human cortex biopsy PSD full list | 1461 |
| L00000071 | G2C | Homo sapiens | BAYES-COLLINS-MOUSE-PSD-FULL | Mouse cortex PSD full list (ortho) | 1556 |