G2Cdb::Gene report

Gene id
G00001420
Gene symbol
GSK3B (HGNC)
Species
Homo sapiens
Description
glycogen synthase kinase 3 beta
Orthologue
G00000171 (Mus musculus)

Databases (7)

Gene
ENSG00000082701 (Ensembl human gene)
2932 (Entrez Gene)
69 (G2Cdb plasticity & disease)
GSK3B (GeneCards)
Literature
605004 (OMIM)
Marker Symbol
HGNC:4617 (HGNC)
Protein Sequence
P49841 (UniProt)

Diseases (4)

Disease Nervous effect Mutations Found Literature Mutations Type Genetic association?
D00000194: Alzheimer's disease (late onset) Y Y (11326302) Single nucleotide polymorphism (SNP) N
D00000166: Schizophrenia Y Y (15719395) Single nucleotide polymorphism (SNP) N
D00000170: Bipolar disorder Y Y (16289783) Polymorphism (P) N
D00000191: Parkinson's disease Y Y (16315267) Polymorphism (P) Y
D00000170: Bipolar disorder Y Y (16528748) Single nucleotide polymorphism (SNP) N
D00000170: Bipolar disorder Y Y (17357145) Copy Number Polymorphism (CNP) Y

References

Literature (424)

Pubmed - human_disease

Pubmed - other

Gene lists (5)

Gene List Source Species Name Description Gene count
L00000009 G2C Homo sapiens Human PSD Human orthologues of mouse PSD adapted from Collins et al (2006) 1080
L00000015 G2C Homo sapiens Human NRC Human orthologues of mouse NRC adapted from Collins et al (2006) 186
L00000016 G2C Homo sapiens Human PSP Human orthologues of mouse PSP adapted from Collins et al (2006) 1121
L00000069 G2C Homo sapiens BAYES-COLLINS-HUMAN-PSD-FULL Human cortex biopsy PSD full list 1461
L00000071 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-FULL Mouse cortex PSD full list (ortho) 1556
© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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