G2C::Behaviour

PSD-95-PDZ3 knock-out mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 16 behaviour variables

Mutant mice showed very large overall behavioural difference from wildtypes, with six of 16 behaviour variables significantly impacted in these mutants. In the elevated plus maze task, two behavioural variables of five were significantly impacted in mutants. In the open field/novel object exploration task, one behavioural variable, OF NOE total distance, was significantly decreased in mutants. In the fear learning task, one behavioural variable, fear learning tone effect, was significantly decreased in mutants. In the contextual memory task, two behavioural variables of two were significantly impacted in mutants. Only rotarod and cued memory tasks were unaffected. Definitions of variables may be found below.

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The G2CMine data warehouse provides cohort summaries and individual mouse observations from the PSD-95-PDZ3 knock-out line phenotyping.

 

Variables shown are: EPM total distance, Total distance (cm) travelled in any arm or central zone of the EPM. EPM max speed, Maximum speed (cm/s) travelled in any arm or central zone of the EPM. EPM % time in open, Percentage of time in the open or closed arms of the EPM spent in open arms. EPM time in centre, Total time (s) spent in the central zone of the EPM. EPM max speed, open vs closed, Difference between the maximum speed (cm/s) observed in the open arms and the closed arms of the EPM. OF, NOE total distance, Total distance travelled (log₁₀ cm) during initial exposure to the open field and in presence of the novel object. NOE vs OF distance travelled, Difference in distance travelled (cm) in presence of the novel object and during initial exposure to open field. RR naive fall time, Fall time on accelerating rotarod (log₁₀ s), naive performance in session 1. RR learning, Learning on rotarod, measured as increase in fall time per trial (s/trial) in session 1. RR memory, Memory on rotarod, measured as excess fall time at middle of session 2 relative to middle of session 1. Fear learning, trial effect, Fear learning, measured as extra % time freezing before third trial compared to % time freezing before first trial. Fear learning, tone effect, Fear learning, measured as increase in % time freezing due to third tone compared to increase in % time freezing due to first tone. Contextual memory, mean, Contextual memory, measured as difference in % time freezing during first 120 s re-exposure to the box compared to first 120 s in the box on previous day. Contextual memory, change, Contextual memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the box. Cued memory, mean, Cued memory, measured as increase in % time spent freezing during 120 s of tone re-exposure compared to increase in % time spent freezing during initial tone on previous day. Cued memory, change, Cued memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the tone.

 

Variable Units Wildtype M (n=8) Wildtype F (n=6) Mutant M (n=7) Mutant F (n=6) P(sex×mutation) P(mutation)
EPM total distance cm 680 (54) 858 (70) 447 (145) 542 (116) 0.69 0.014 *
EPM max speed cm/s 13.7 (1.1) 17 (1.1) 10.4 (1.8) 13.7 (2.3) 1 0.057
EPM % time in open % 58 (14) 49 (11) 67 (17) 68 (16) 0.75 0.38
EPM time in centre s 153 (17) 166 (17) 89 (21) 65 (37) 0.44 0.0024 **
EPM max speed, open vs closed cm/s -2.1 (2.2) -0.8 (1.8) 1.7 (2) -0.4 (4) 0.52 0.38
OF, NOE total distance log10 cm 3.12 (0.08) 3.25 (0.13) 2.71 (0.06) 2.96 (0.04) 0.45 0.0002 ***
NOE vs OF distance travelled cm -437 (270) -183 (92) -88 (42) -91 (53) 0.46 0.18
RR naive fall time log10 s 1.12 (0.07) 1.43 (0.15) 1.24 (0.05) 1.16 (0.16) 0.089 0.62
RR learning s/trial 0.5 (0.6) 1.9 (1.8) 0 (0.6) 0.9 (0.6) 0.78 0.44
RR memory s 4.6 (5.6) -6.6 (4.6) 10.2 (6.9) 11.9 (4.4) 0.27 0.058
Fear learning, trial effect % freezing 42.3 (9.3) 75.9 (2.6) 50 (7.6) 50 (11.4) 0.064 0.41
Fear learning, tone effect % freezing 13.1 (6.1) 3.6 (4.1) -15.3 (9.6) -16.6 (16) 0.67 0.017 *
Contextual memory, mean % freezing 50.1 (7.3) 42.8 (3.3) 8.7 (4) 8.9 (2.9) 0.48 0.0000002 ***
Contextual memory, change % freezing 28.7 (7.5) 52.2 (12.3) -6.4 (6.3) -9.2 (10.2) 0.16 0.000027 ***
Cued memory, mean % freezing 4.1 (10.5) -5.3 (6.3) 4.7 (3.1) 9.6 (9.5) 0.39 0.4
Cued memory, change % freezing -0.6 (9.6) -16.5 (10.7) -7.4 (10.1) -19.3 (8.6) 0.84 0.62

 

Elevated Plus Maze Performance

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Variables shown are: EPM total distance, Total distance (cm) travelled in any arm or central zone of the EPM. EPM max speed, Maximum speed (cm/s) travelled in any arm or central zone of the EPM. EPM % time in open, Percentage of time in the open or closed arms of the EPM spent in open arms. EPM time in centre, Total time (s) spent in the central zone of the EPM. EPM max speed, open vs closed, Difference between the maximum speed (cm/s) observed in the open arms and the closed arms of the EPM.

 

Variable Units Wildtype M (n=8) Wildtype F (n=6) Mutant M (n=7) Mutant F (n=6) P(sex×mutation) P(mutation)
EPM total distance cm 680 (54) 858 (70) 447 (145) 542 (116) 0.69 0.014 *
EPM max speed cm/s 13.7 (1.1) 17 (1.1) 10.4 (1.8) 13.7 (2.3) 1 0.057
EPM % time in open % 58 (14) 49 (11) 67 (17) 68 (16) 0.75 0.38
EPM time in centre s 153 (17) 166 (17) 89 (21) 65 (37) 0.44 0.0024 **
EPM max speed, open vs closed cm/s -2.1 (2.2) -0.8 (1.8) 1.7 (2) -0.4 (4) 0.52 0.38

 

Open Field and Novel Object Exploration Performance

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Variables shown are: OF, NOE total distance, Total distance travelled (log₁₀ cm) during initial exposure to the open field and in presence of the novel object. NOE vs OF distance travelled, Difference in distance travelled (cm) in presence of the novel object and during initial exposure to open field.

 

Variable Units Wildtype M (n=8) Wildtype F (n=6) Mutant M (n=7) Mutant F (n=6) P(sex×mutation) P(mutation)
OF, NOE total distance log10 cm 3.12 (0.08) 3.25 (0.13) 2.71 (0.06) 2.96 (0.04) 0.45 0.0002 ***
NOE vs OF distance travelled cm -437 (270) -183 (92) -88 (42) -91 (53) 0.46 0.18

 

Rotarod Performance

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Variables shown are: RR naive fall time, Fall time on accelerating rotarod (log₁₀ s), naive performance in session 1. RR learning, Learning on rotarod, measured as increase in fall time per trial (s/trial) in session 1. RR memory, Memory on rotarod, measured as excess fall time at middle of session 2 relative to middle of session 1.

 

Variable Units Wildtype M (n=8) Wildtype F (n=6) Mutant M (n=7) Mutant F (n=6) P(sex×mutation) P(mutation)
RR naive fall time log10 s 1.12 (0.07) 1.43 (0.15) 1.24 (0.05) 1.16 (0.16) 0.089 0.62
RR learning s/trial 0.5 (0.6) 1.9 (1.8) 0 (0.6) 0.9 (0.6) 0.78 0.44
RR memory s 4.6 (5.6) -6.6 (4.6) 10.2 (6.9) 11.9 (4.4) 0.27 0.058

 

Fear Conditioning Performance

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Variables shown are: Fear learning, trial effect, Fear learning, measured as extra % time freezing before third trial compared to % time freezing before first trial. Fear learning, tone effect, Fear learning, measured as increase in % time freezing due to third tone compared to increase in % time freezing due to first tone. Contextual memory, mean, Contextual memory, measured as difference in % time freezing during first 120 s re-exposure to the box compared to first 120 s in the box on previous day. Contextual memory, change, Contextual memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the box. Cued memory, mean, Cued memory, measured as increase in % time spent freezing during 120 s of tone re-exposure compared to increase in % time spent freezing during initial tone on previous day. Cued memory, change, Cued memory, measured as increase in % time spent freezing from first time bin of 30 s to fourth bin of 30 s during 120 s re-exposure to the tone.

 

Variable Units Wildtype M (n=8) Wildtype F (n=6) Mutant M (n=7) Mutant F (n=6) P(sex×mutation) P(mutation)
Fear learning, trial effect % freezing 42.3 (9.3) 75.9 (2.6) 50 (7.6) 50 (11.4) 0.064 0.41
Fear learning, tone effect % freezing 13.1 (6.1) 3.6 (4.1) -15.3 (9.6) -16.6 (16) 0.67 0.017 *
Contextual memory, mean % freezing 50.1 (7.3) 42.8 (3.3) 8.7 (4) 8.9 (2.9) 0.48 0.0000002 ***
Contextual memory, change % freezing 28.7 (7.5) 52.2 (12.3) -6.4 (6.3) -9.2 (10.2) 0.16 0.000027 ***
Cued memory, mean % freezing 4.1 (10.5) -5.3 (6.3) 4.7 (3.1) 9.6 (9.5) 0.39 0.4
Cued memory, change % freezing -0.6 (9.6) -16.5 (10.7) -7.4 (10.1) -19.3 (8.6) 0.84 0.62

Acquired (raw) data

Animals tested in the G2C behavioural phenotyping battery

Cohorts are summarised by genotype and sex, followed by a list of all the animals from the line tested. Shown are the unique radio frequency tag id (RFID), Genotype, Sex, mouse batch identifier (Batch ID), date of birth (D.O.B.) and data of RFID chipping (D.O.C.) for each mouse.

View experimental protocols.

 

Behaviour Cohort Summary

GenotypeMaleFemale
+/+1411
-/-1012

 

Individual Mice

RFIDGenotypeSexBatch IDD.O.B.D.O.C.
089047559+/+FBATCH_06-03b12/08/200620/10/2006
089256582+/+FBATCH_06-03b15/07/200620/10/2006
089539097+/+FBATCH_06-03b03/07/200620/10/2006
089549270+/+FBATCH_06-03b13/05/200620/10/2006
092539570+/+FBATCH_06-03b19/08/200620/10/2006
015881264+/+FBATCH_08-4223/09/200827/11/2008
011382799+/+FBATCH_09-0104/11/200807/01/2009
011076315+/+FBATCH_09-0817/01/200912/03/2009
011099542+/+FBATCH_09-0817/01/200912/03/2009
011318606+/+FBATCH_09-0817/01/200912/03/2009
015879587+/+FBATCH_09-1722/03/200930/07/2009
089075860+/+MBATCH_06-03b19/06/200620/10/2006
089258831+/+MBATCH_06-03b19/06/200620/10/2006
089547119+/+MBATCH_06-03b03/07/200620/10/2006
089638317+/+MBATCH_06-03b19/06/200620/10/2006
089082380+/+MBATCH_07-0102/01/200720/03/2007
089621126+/+MBATCH_07-0105/12/200620/03/2007
014263550+/+MBATCH_08-4025/08/200808/11/2008
015879546+/+MBATCH_08-4210/10/200827/11/2008
015893314+/+MBATCH_08-4210/10/200827/11/2008
015875826+/+MBATCH_09-0422/12/200830/01/2009
011063637+/+MBATCH_09-0811/01/200912/03/2009
011079101+/+MBATCH_09-0811/02/200912/03/2009
011038040+/+MBATCH_09-1112/02/200923/04/2009
011359621+/+MBATCH_09-1112/02/200923/04/2009
089041359-/-FBATCH_06-03b19/08/200620/10/2006
089066083-/-FBATCH_06-03b19/06/200620/10/2006
089120104-/-FBATCH_06-03b12/08/200620/10/2006
089516069-/-FBATCH_06-03b10/05/200620/10/2006
089559577-/-FBATCH_06-03b23/08/200620/10/2006
092277346-/-FBATCH_06-03b15/07/200620/10/2006
014274021-/-FBATCH_08-4025/07/200808/11/2008
016552635-/-FBATCH_08-4223/09/200827/11/2008
011348549-/-FBATCH_09-0106/11/200807/01/2009
011382515-/-FBATCH_09-0104/11/200807/01/2009
011036882-/-FBATCH_09-1722/03/200930/07/2009
011054775-/-FBATCH_09-1711/02/200930/07/2009
089269820-/-MBATCH_07-0105/12/200620/03/2007
089305535-/-MBATCH_07-0102/01/200720/03/2007
089358549-/-MBATCH_07-0105/12/200620/03/2007
014117355-/-MBATCH_08-4027/07/200808/11/2008
014118102-/-MBATCH_08-4026/08/200808/11/2008
014122873-/-MBATCH_08-4026/08/200808/11/2008
015890079-/-MBATCH_08-4022/07/200808/11/2008
014113816-/-MBATCH_09-0422/12/200830/01/2009
011379335-/-MBATCH_09-0805/01/200912/03/2009
011027004-/-MBATCH_09-1122/03/200923/04/2009

Elevated Plus Maze

File NameSizeChecksum (SHA256)
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089549270.mpg12566528ca0ca4854b2251eda873d16164e584a8185e368f0826fbad7b53700bee8d5734
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089041359.mpg11849728034330124a2718833723665cebc5d6cec3c144e84764dc8ee85a8ea2f9a7209c
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011070116.mpg938188869fd1c4c2133c547a642aff0a1107c35346cfd10e3fbbfa86d554fef075652a9
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014117355.mpg97300487d02b1ce25054cf2f033f214baa6e49b378357f70ebce7e9d08493e3a00e7c99
016566364.mpg9537536ef22d7a3c1eacd58468d7159376e057002cdceae0e29c9189b7eebd80b0b396c
089256582.mpg1361100899239af0267b3d3e1e1d2a436290e70eca0a2a2abe657044d34b2589d561724c
014274021.mpg96808969e5262f785b42630891ce815c2f0f7b5eb0ac55d2de19e4ecc900ecbb8a64dae
016551518.mpg9981952f032edf161d2a3958fa219d39475843681056e6f7b9a8f5c36ed966c35ca74ba
011382515.mpg9435136bb892ae66a48c678df1a8b676d795f9a0f1179ad0ec40ff106f451c0e7d279d5
011054775.mpg9930752a2c32c5e788b5f8b317a99184215457245a367aa01642e770225176b11729d06
016546348.mpg10207232067059b1e808f33044d3f1521bf89560b60cd02efbedaf431ff5bd7b5629a567
089258831.mpg12240896f962186a67bd1f8859ba8572cc1597eb0ae7d12e672e4449f056adb01c9a6653
015890079.mpg9891840c4a1b3d84533ebab25bdadbb81984e512eb3939b7f2d642662ff69a117af6e7b
089066083.mpg1139712008e7d58a52a3bdc4cbbea876ff3e7468cfe8d6a009cadddc880e1b036ea574d3
011079101.mpg972185689048b9631e8c8b5499590a5a96b24595dcfad41fd92182dc008f1ccfd51f894
089547119.mpg13903872c468ff4622a1741a98c464c458d1783e314013617f513cd299296a154065b6a5
089305535.mpg592691257cb4a9c0664f636f13ac817464dca59ec3ee9b340bcd72022a5e5cb052aa057
015893314.mpg9850880f7f0eead370821060ae59ff205465a03b89d15bc5854a512f5c5b2330eb7de3f
089075860.mpg116080645f0d8b611a3ce5350c43aa93a95b5bdd2a27a4f3f176f053588b0785e604c391
089516069.mpg131358722c4ece281ea0166f06e57aafd76e522fb458a7a9efccae2b3f2ec95427d0913c
011063637.mpg9994240c686ef25dade78ad52480fa685393c57f61b5f21f5b083e1ad00129247512e9b
092524293.mpg12144640c497d1a733be1318ae8d7317023199d773d0fdd1420532863d4c310c82dd758f
014113816.mpg1145036891c9ae5ba196a6fc078ae1d260a9eede5abced7ba56e4401e1a3922d1989a061

Open Field

File NameSizeChecksum (SHA256)
089559577.mpg1681612898614897d7625055d4e2278e510eadc35b869630edde9418e3895598d3af6a81
016581780.mpg8325120ea82790900040ab9ae6d67cda821587261d61f7708ac44ef7401abf98233787a
016551518.mpg103075848bb011d59b17575933c298b5424d5d45c17a57081e9c031bb8fd0516c998a090
015879546.mpg8390656c556180023a277aebc5bc9aee3ecbbeccf01db9659911aef5c39bc17779852db
089638317.mpg9453568d1473733b55d93e00dc121b028277bb9835bc6129047836b2f2c2422b5731f62
089041359.mpg12855296dfb1b91e12dcf5f99257d6e9aacc0937657d73e9dabbe91e94e6a027f31bab67
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089082380.mpg116879368f144c575448d80aeb0f1bd5f769ee9fad6522282f629fd54cc7e62078be9938
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089258831.mpg8992768219e1b2bf5c62090134da8eacea71b0d6957cff476b83ffdf74560b5f80c209c
089047559.mpg9039872d78aedf345fe96cf3f5c4f9eb3bcc407d622b3a6c422ec1553224ef5c0ac921c
015879587.mpg8392704fd62a27e415990e67ffabb625eb67b082ccc114d107f2fb539ec90de6ca02489
092277346.mpg9480192816b348e2be53902288504602c46d0ae4c294aa3e693bff8a4143eb869a25b35
011054775.mpg10911744812807841ee65d189959ed56ffef32d4ff1e5ff1153de34ff37e60b90947d565
015881264.mpg8833024a2ed511357a820778f30dd1de545883cc70647ecfc5e12f32244787ceb383419
016546348.mpg8378368175fddf58d7e9a2b002ceef254fff7c9d36aa7e071269e7bb346eab07ec8da2a
089358549.mpg853196855fb566d4b7a22a251aa92bd4abc9ed819c6851240e6ace59068a9d1e685f31d
011359621.mpg9072640110985e21e07142c789c5d1f84b3a686a843a453f40827ff61e04037d13e0c06
011076315.mpg90849289a3a052c9f251cb4eb3a977020fb80c5b5274e89e9b430b94364e22c96474768
089621126.mpg11145216b8bc1579a25292d6be1cb9d877ae97530c0f59ee09a8cf35e7303aa3502f57ce
011038040.mpg105717761bf1e90d6237d43e9d8d228cd2222731ea176d47ddee1fe9c65189bd8ebdf770
011036882.mpg107499522b4b52acf982ce34f6871fa72acc8bc174aadb7a9274fea5deaa4e0529edb52e
092539570.mpg96481286cafdd5d3e49b0cbb861dca4092ed82af1eea18c695da836c1e759603e5f48d8
089256582.mpg12503040e35904c9acd2691f71b7e0a60acc49a0234866c4a25f93eac33262db87bf6032
011068771.mpg10526720fa4c7d93af000cb90852d5c6dd10635d47b7af943c248d52fb20db5d54766e66
089066083.mpg138485760b2a80aa416985c3e922530895f17bcc255ad239ba84a88b9c672bfcbf9ae6d9
014263550.mpg8491008297316192b2581af592c54600c66a34989bc329add2639bc1b766be5c9f1a9cc
016566364.mpg1052262412f8d0ba2278111742b73ae7f09bce26375c815a031c0cf041e1c932e6a79019
089069267.mpg12546048f518685e68acdaf559d460a13f255694e708466399a52b0fc0e84feaec4f9657
089305535.mpg944947288cbc6d1c667208dce2eb7b067c0e52508215a7198da5a3159ff078196e447e2
092524293.mpg12879872891293d602a16a7da89dc99a6669b62c471ee3bd8154c0b621f994eb9ed1794b
089120104.mpg118435841437cb386ddf613c46bcbd21289e9fea95657c4c233d34dd5ca82d5134dbe826
011348549.mpg88514565d3b3c2cd9671eefd57095167d07ad4e85c153822de7daefb35e890ad84ab91a
015875826.mpg10489856281923cd13662a2516352d858e0a2a50a6cba17cb949b9d95afd04a04d5fc899
015890079.mpg84172807d629de9d9cf72db0e3aa24faf20c8d4baca22e3719bd6c7bf8091728789b942
089539097.mpg1041408028d14fdd99e283b26c234c50d42c23fcc474cbc48dc75533173ada212ef9e575
089269820.mpg89210883d869838892947d7d5fc8dc22a40116d042d6fe27a0f377e95e99d3b6bacb1ee
011382799.mpg1102028885fa87d58c9ffb9bea41464f1b3a0c329f4027d8f1a97c1d279bb024ba400b41
011097370.mpg86773762f294bf6a1dc086ea21237e160587a202f32bb202ad0095ef1a457a78eb91f7d
015893314.mpg10475520c8fe0e832445e94fdfdcecfb764ce877f74853a9fed5eb010dcca20d4f4397d5
011070116.mpg8515584b00c7ce65a9aea806c7b4c3a58f0ff76a0205e234d5a006170dd20ae6110a1bd
011063637.mpg105574404af18a36d9c793f4017117c841eb54b3a51e3d4691697c6c4a16b9b765d25b15
014274021.mpg82391049a83c8635e43ec283a02981b09b50476efe1b461df9357b38995bb60c26c750e
011079101.mpg1063116898a74444187e985e9c60d4ad4f8cc3f512803caeb9cd597cd757d93124e80d8e
089075860.mpg11978752ba0bf121dd61bb8ae29bc2e9c7a79a56e7ee83a41ebe045049b27ea529299b79
014122873.mpg10610688d246cce3122fefe2826b4c5610bea9b4472cba15eb2befb107b7d1a355bd350a
011379335.mpg8468480922e06b798434f7815c7ebb078db853e8affc2deaf765f5b8d51acc35c26930a
014117355.mpg83210243d7d1ecfeb78c7f49e0c9febd2e241b80ce7e2683a7debcff4275a5a78c6a97d
011027004.mpg88924165659f0d42b9fa97dfff67294199b512b749d52c0dc5ac1b95a41ac307242669a
011318606.mpg11055104f18dcff99f037aff555b855acf4f895c57b3fec9f1c8718833ebd1d9c5db914f
014118102.mpg10612736ed3ef95ce43e202a87d5c05ff49f62706dc7ed1cceab8addb0d4b38dd6c11db2
016003831.mpg103874568b48e08932c856fc08e8fd927384620be7c7881dae95e05e78c73338aa0cebb8
016004555.mpg10416128f0b39e0ac2aac29aa906a683ffc8cb09eeb86220751bd45a76404301fc1367b8

Novel Object Exploration

File NameSizeChecksum (SHA256)
011068771.mpg10815488eb0bff6555cafa990d13cd6b8e18181bb13c4e5bf8601a80c55dab809dad3920
011382799.mpg908492803192659d674f70e98d10ca490ef904b5ad2e8022042c124ecdf71dbbbee4949
089256582.mpg1338982437800d56fe6755db82c6828ce6434fd8091ed93506be1bfa781ee30656bc525a
015881264.mpg8380416d9346f382846aaf13f5def29841d130592117f3963e6b84a5742c2922bad4666
011318606.mpg11255808b60d3dd7c021924edb72369110ceb3619f961f0f0180ee88e24dfb7bf0039f1b
089547119.mpg894976003936ecfaafcb13d79cd0d0f701916d3455ad5ca143c1ef1e885754549914011
016566364.mpg10473472d0d40b29392491191904248a0422578612b25444458a0c36243e884beb2c95d4
011036882.mpg10788864d462c1e50938907ed55856e5c52a6e71aab38f588db8a15249e93cd672ff470a
089516069.mpg12034048a808d3b6ce50dc5a517a2f891a578b6c406f2876b03545873430d32ba5eed7f9
016004555.mpg11583488db3b22d31d369b3f0d8b0c431f1020c21b62f646b89604ea1b667386f76d9ea5
014113816.mpg13053952cd86203c193cddb4ee12e25b9642a23e1a5555fce43282c892d8efb2683c304a
089638317.mpg885760059d53af4282047abe048abb9674e04851f2237907129fce778eaaa2e7988fa48
089082380.mpg11585536f75f9305c9efbbfe467fc4a23ee4e15722ba1fc96330c4240728f7892584476e
011359621.mpg8953856e514ee6049b96d3fc312f96c7a21a2873fc34a6bda44ab869cba18d0b535b8cc
014122873.mpg117043204af5ec35b349c7eced012282f13967fc8fddc02101129fd21475a2b057636b30
089075860.mpg12060672fe47f749e9993b0c93a02ac89c851aa712340f391be2c96b58b1e7bc00fc32ae
015893314.mpg10702848566fa5829f3c74aafc61d758d6e5cb0e729dd3bfe9f9a04cdbabeb5ec6c42de9
016551518.mpg10553344ecb7a2fc3df49e6e2d345d7a8f4f6aed4143bd3e5d982aeddce7a94a364c04a5
014263550.mpg91873285b90581808838c0124ce261131d11a9f466331135531b983f1b4279142f4d424
089559577.mpg122368008484df4d15bfcffe90dafc1e149a6c44785898648fe604841991f934c6f4ae88
089358549.mpg11026432e748a6e1641c8882ae197f37ceded01bf68868f74dc5fb4325fd148f0a47d523
089539097.mpg9308160d1a5a977a1489477415b3dc504f77de2319436a143dd12671328dba235c5b916
014117355.mpg8298496e5a10ca2040dcd739dfb73f6606fb2c82c5f145c7f9577847841cc63dcb9b10e
011054775.mpg11714560b42c40005290d2e74a50cba3192d17645cbd6b5762e9682112988a521dbb0c0f
011079101.mpg10717184a12cd96686f150f38916745964599c4f5c9fa91cf6a812a6042c8973f542d950
089269820.mpg8732672c94793908db8202055ddfb5780ac131c0853389e9f7cce62728f621c01396f5e
089066083.mpg1248870462838a0cdc77d3aa89cf98d55515bba6b542e112c7c7fd5801809d10675d5eba
011063637.mpg107110408eeeab36c77b02f88355393098cc36f8033af04a527d57151a31cc7d6dcd9777
015890079.mpg9089024ff01966bd96bcd687ffe9440b0e1f0faad7860cccfc5c8dfc80b91ad54ce9805
014118102.mpg13807616503f7c5e6167b2b001834f46c0aa55311c418120becbbe56f5fd34838b4a75bc
089041359.mpg12156928c935187f20d76024d3de703184b11e36339d467dd673cd464bf0be93f0649965
011076315.mpg8974336403f89426456eb5cf2b53bca4f30826d3a3a7192149ef75ed846556b421f41c7
092539570.mpg9160704660955d4568d64d691ad9fcd79d7314ed4b0b0c91f2139d17e357bfbbe6dac98
092277346.mpg9865216b0bf7c9b089a624642996df66567333d31c48aa4bae3945563d909cb6f364557
089305535.mpg8728576cb79f1b1009fb84dbf8655057feb9dc7fc8aca4c10385f9763a267960961e80d
016003831.mpg10588160be9cb9502c1fa0fc272811c99f85895bc9cafaabe6c4765c2133bca5824d826a
011038040.mpg105205764f3cb397e252ce6a18b93485240e13a21491ab986a26d48f1567d4649f3cacd8
089258831.mpg90173448643776d0b9fad1b18b18a9124513bbaad5db8994f50023aa7c1584c926922b9
089549270.mpg118743042a00e2c0650168c9286862e53975ea76422fc2280c7b9cbfd0c5198dc5ae52bb
092524293.mpg9209856c55b72b4850153b64b06ca2bec4fe6a1757a74a4ea280b7440781b36491cd535
016581780.mpg8325120cdfafbd7ee692554af98c2ecb18f5155ad63f3a3f616f157255e84e4bc811c9d
015875826.mpg13047808ecc43e937677e61a668865461a3afe02317acb3844f805f7cdb0030d92c14845
014274021.mpg8394752e39f0158cf47f89afbc76fc42c63bb0f67bce0be4f61ace0d20d5cdb89db1fa4
015879587.mpg91648006ebea4ffe0a34e6c78e840940c99007a86fbc4e2115a6009290b7dfa02eaf68f
011099542.mpg10563584df5c3173ccc333b1b1909d1cf1ec492c94d0075a754bf8d62465e0296e55d328
089069267.mpg116797446e3bb15a7964cb5e2da98a8bd08091b1ba40c8200484174c4a55648c808cd7f0
011382515.mpg111349761b3ba2e138adf315507caf0c747a38f3404d311befb0f2a3091221b24f5e67d1
015879546.mpg85975045984f344c9ee338d6d3fac83bb5f290871b2cd43dcceff7cd48053b653c997f5
016552635.mpg103362565f5629e93efd8389db15a525e59a5a870bdeafc58ac216345126cc8f72acdb56
016546348.mpg107479046ea3c2ffb9591903d43f54134b565d56b9991f1f3e9dc34d7cdee1fd91e16d56
011097370.mpg873472078168f615dd67a720ca4aefaeab43e5d08845e8017c568c31a27e999d46dcea9
011027004.mpg91750407cc8b4612cd89c3e99e35a0368e2348dc550427624ab301aacedd63daa4b28bd
011070116.mpg8511488bbfba7de44714758bbd6c61d7c748632122be7be29dc66f1aff1982d738ba7f9
089120104.mpg13240320700b1834ceece4be76d9cafa136725583572644c33e1ad81350a706c69945be0
089621126.mpg14612480778ed988cf2d7b9b180b3ccc81a99a40f758b1dde413ab5d79d7605f6dd06096
011379335.mpg8671232642899bd193b0b06239e6cf6b40eab09d536f8c11bed9cf5347979350063324b
011348549.mpg8615936bae17f916518ab69337163bf25f97a6bd33374178a60f64df66d59c78f5f6be9
089047559.mpg99532809fb33aebb2e6f83a881452d9af0c022c58d6835021bc4a507d6ebed98e031b5d

Rotarod

File NameSizeChecksum (SHA256)
089269820.txt4972bb6aea3dd00b5dba29b0598a78e0d897ce4d500287b7d741de55fc5c070c4cc
089516069.txt499c9fedb6a0ddd93af7b71cc18a8589583a972f2591dc35424df2a6170a851abf0
089559577.txt4961d7204a4cfb822e62f581343eea33e532d802c15c4eb7edc31116cc51f764e79
014263550.txt49002381c754fca8cee71948a34b8fa97bae131ab53c7e36b1ff5c22e2baf644ecc
089305535.txt493bf28bc4a9250feeaae74fb1582d4b5e8948fe200604ed02545c540a67acc60c6
011348549.txt490bf312835d79063007ea88a4277304f4ec485edc3fceebb4265ed2d746d595b4c
089549270.txt4815ec7330c44b3dc20199b60bd154835e0666fcf69c2c8ff2fe30e03f1b692def8
015875826.txt487466ec0d798be1e57135336b1379090f72fa922abf8b3388c8d56c2d590ab13bf
014122873.txt4846e63c7d51afcee86eb507395be650e348a1d676181f338a45ca3c19200493296
011382515.txt495b18062390bdf1e55c810da84f92f7f55403ff3f474a68550748cd8f9d6aa62d5
089539097.txt4872789e60e30ea96624e88d335c89e72b34f124450344b411bd33da07eceb5317d
014113816.txt497af039c20064e602e472db067bc4f57c6fd051758a464a6e14e848b36275e395f
011379335.txt485d98adfc19b46e4cf105c7ec666a3a93062441500ddd7c26927615658fa42235f
016552635.txt499ba7c5f17f0f508e0f906cde074b20483c93b54d579c0974cee032a9c0c3c5a0a
089082380.txt502ddd6a701d547daee5c8990b40c0f44d3a02b8c5009ce5babcf9a2926498e4f3e
089621126.txt49511b9b5773038dc8063626975e9c198620b317a3fe9619fce06c0f488374516be
011036882.txt4897f40d78eb64c0f50ce2387fcf4410c6f90d366429c20de3db6a548a8ed307fcf
015881264.txt4820808e62dc159e273ef78d9640706322111b0ac4941ba957a86b409d444e32d64
015879546.txt482369cc2c6c84d50241f791b098f0b208be29793b1ed65eac7ef5cd1ede82fd543
011054775.txt48694f54e6911422cdf0819ca6ca96b2b4dd916b389e121d41cde1ea3f2b413d1fd
089041359.txt49967e49a119a56a90d3013a271c759098a04ccc3117c82999a12b437faec406561
011382799.txt498b9bd91d99ce8cbf266250e49b68398d60f0723d2c0cc6393feb3d24e4db3824d
015893314.txt4857702b2bb8a66f3cd2ee353a6d45a5ca22b6b4859b006bd6474d8072e48ce4671
089075860.txt507f8717a2a7e92574ff24f45d1dcb0acb82a677e5f96c7f78e7e9f09acec698ed3
011318606.txt49005dae3807d18930115b31dc9a8ffcb6858ddf72691ac3317294e097735a6e3bd
014118102.txt493dc21d7c07ee46442b12bb271cebf9afc2163d52439fd203957a859455b3f34f5
014117355.txt4940d95d536069472187839236e01874394d2945a2492570b1946ca8bdf5b583efc
015879587.txt485346630c54319d05e2eef046267cfc5681f401b70cf091324da6212726b96ffd7
011079101.txt487b9f5679dd0d9c2a0dc82a45cfafc60c595f5ae52ae89fe4842b5a6e3ca7fd0d4
015890079.txt49503a68b75c9a224284b9f9dc0905ccee83131a700296c48357e7bc9e31d579411
011063637.txt497d1a6d3e2ba5b2b4d5054f5a2245e97a41e88a6ff7db830a692d2bff2732a7370
011076315.txt4956285efe849eae341dd5fe7da226d2a4841765d036cd2bb819e17440b3fc6657e
089066083.txt507c1e9b66aa5b616b762c0744234f8c42dea7dcbe443a733853f5151c2ff7aaa9f
089120104.txt490a0a42a286cdb1daaa36889c49b84d9a3e7b8c75c7d022dc8edf1c6d46461ee44
011038040.txt484f0139629b90e81cd1b0958d54ae6ca78dad42592fe32c262efb4c5924f7a24c2
089638317.txt490f0f75de8929ba7f1d5924ea937c17c2211c310f76fb8d61749868bd5d023d099
011099542.txt5024b335718cad0a3de4a4ae30632d066125ee4436b1c5da5f774c052b8eded6645
092277346.txt499017cf0ff37303e7375ea665dbf6bee570b0b567c81a32bb3c7f97f9a8e28ca85
092539570.txt506fcd78bff38e6a256c6295f9f49ae63b45734984d894c5e7d6ec342e44994df11
011027004.txt496be74b602c4238179a7b3fdffc460cd48340efef969bbe1b8d75d21be541b54a3
089047559.txt496f7f20eb620d9c1d1067a09b7f2caf320ba7684161dc6f3aeacfde427f0ecec71
089547119.txt4982a2aa7a7a1d7df0c190afabbf959b9e7b125a8835378574d2dbedc4e8c583514
089358549.txt506cb6f3a1a95d8b08833a2f1026284db242be19fa8a172c2c83e3c9b2d0aa44c53
089258831.txt493bd26aa28c778aae8fafdf345e5a2e15d80d0be5faf4a884416f54535a20f0803
089256582.txt4934a999594f4f89d6278160f26c596e76c4418e913edc3cb88ecee3e7e3fbe1b26
011359621.txt48985b028babae7ef3bea600a8b7e21761d49564afc9538f3c3567d6dc698114e5b
014274021.txt488bcca493b717a89e7e44452c51fd3911a75389a27a6e0be2dfb280716185614f8

Fear Conditioning

File NameSizeChecksum (SHA256)
011379335.ffii113894640a140ba1da1d55c20e6e986ddc69f44a0fdd14089e86f5fcb00c59254eb18b2f8
014122873.ffii113894640ba36193bf0bfd6b75b135b6013eb09770bfecaabc3f1787a2a41e0554769122f
015893314.ffii1138946404da6f9a02f5216fcbe7cdcb36295ae9486fdedc03b6416518c26726844b62219
011348549.ffii113894640af2347f371f64f48c3271733dc7569906c89e2efab35e601befc2233dee17405
015881264.ffii113894640d7e41401bd0986ba7b2f7363e45f721e25e80ba144c402b8aa0b7b872493486e
011099542.ffii113894640f5a747db07b574a787ca9b4ba94735d84fcfd6edc53af6a29037ea67efbd02fc
015890079.ffii11389464036b4efaa54bfcbbc6d2af6b8454114644bb0bd7bab30c3a2e5f1bcaa98746b52
011027004.ffii1138946406778b2de2b69cac2c7bfa73ddc992c370b0e3cc14762adf0692ea305ba3f08ef
015879546.ffii113894640bed1d1136f30b82997df2167c9cc93b123d33c4ec68d1665bfd13c84b82a0039
014274021.ffii1138946408eb198a7627047bb37a73ac8415aa40c7f93501a2d6fa3b55d5cbb33eda6c8fd
016552635.ffii1138946402101746d013e90e9113e411ad39a0241d9e61e98e35cec220a03ac91601d8db6
011038040.ffii1138946405d28c16166283e4fb987c5a83ec986c758ca0326134c7130c0b4de6adcf03cc9
011076315.ffii113894640db15671d71aaee9b3326e6acb698b931832fd4f4c64e81d8b65408d3a0a12af6
014117355.ffii113894640c638f9fccf9c3227943d91652084792fe2448e99925fe02962be76db6416e5b3
011036882.ffii1138946400b41474337586ffe0cb02bf2012d154abede11aed5b3b3b8acd70c369e74babd
011063637.ffii1138946404d83a67072d7a0ffac20e60a00e5b74fabc80d2eea0a601b3eccf532040b49fa
014113816.ffii113894640fbcbcf3167715da6179b7952a6a1194b3a4dc58d6852d75cc38745d376288ecb
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014118102.ffii1138946408d9334a3c414bb32090826f6cb4ddbe7c2c2c9642db1f3ed4a0bf2cdc828c8e6
011359621.ffii11389464079754d507dc6f7b9a5501d6d33b36a432eb4e9c90b9b20ebf424d2b974f16363
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015879587.ffii1138946404c61423431839534be3295e41823455ec62f3dbd9b73e0ff52787773266b22d8
File NameSizeChecksum (SHA256)
011382515.ffii840823201e8a844d2c67ff3f7c57cc2854c655fa64bf7c10e6f6d64cf577a41cd2b7a9b5
011099542.ffii840823206afe89e6bf6bdb9d57ad50cd2c65074fc3ac9c849355b653d71a8f566bdf26ea
011382799.ffii840823203588db60a397ba008a5dd4a9d819a7135b54e099c36a2d3ddd69eae7c6e9b0c3
014113816.ffii8408232054c008ec7d64d8bac237adea7d360f6c5e70f1ece4eab2c842b5722297f5c635
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011063637.ffii84082320e5f91113d02b012649c07d3432d435a24d9af92d96dd7be1ad65647e91083c63
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015879587.ffii84082320b40dea44874e3175327e40b7778eacdc1986f0ca68b1358b86d937224b9cbff1
014122873.ffii8408232072fffb24401cc2a3d4951def793d5728abf74c40a531c4add40b405afb0fa368
015890079.ffii84082320602c4f7ec7163bda0e41c8f9e68019bbeccbbbf0aa31155063df68db66922452
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015879546.ffii84082320dfe9d23b6ed3e86c451189123c93c216e242f7aa2f5ab5b87c41caca1c7a6ca1
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015893314.ffii8408232013b570e6eb26e5615699c4e4ec2a70a0cc712b4b918a6fbb7506e70aadea3fe4
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011036882.ffii8408232089c5c4e1102d71333fcedbf081b5182260abefc9623ec3cc516f519910e3654b
016552635.ffii84082320abc95ef89649c0ea66dea6b29e54f68c28ac77bfd7bf38bfb61358b25b54eb32
015875826.ffii840823206de9ef692d3ff4a8b79be8b18ff2b12c2eb81e9528a32c7fa2da7133509b25d3
014274021.ffii840823207c33fa58dac40b199d25016dd46cc188758a41911613a840109bc207a39732d0
011076315.ffii8408232025d17524f8551a2cbb98ae46166ea2c87f680f0ad82ddea641c369def08d17a5
015881264.ffii84082320e1f10b7e7dfe28f45e8d1a14d9705387cb5a63cf6bdc3166b5894dff0da35b9a
014263550.ffii840823203cb677b30c52f43e234be298c8423b9bb9a15e3e6448d5f7a451af4db009516e
011359621.ffii8408232005bf6abcc593060bf672f74cd595531a99a7e7e3d60ec3264ae6995717debdc4
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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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