G2C::Electrophysiology

NR2B-dC truncation mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 18 electrophysiology variables

Mutant slices showed medium overall electrophysiological difference from wildtype slices, with two of nine variables significantly impacted in these mutant slices. In the theta burst stimulation experiment, one electrophysiological variable, burst 8-10 ave amplitude vs burst 2-4, was significantly decreased in mutants. In the long term potentiation experiment, one electrophysiological variable, LTP based on amplitude, was significantly decreased in mutants. Basal synaptic transmission and paired pulse facilitation experiments were unaffected. Note that in the theta burst analysis, the tenth burst is analysed as representative of individual burst amplitude. Definitions of variables may be found below.

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The G2CMine data warehouse provides slice group summaries and individual mouse observations from the NR2B-dC truncation line phenotyping.

 

Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude. PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio. Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4. LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 34 (11) 3100 (81) 49 (15) 3088 (72) 0.39 0.92
PPF at 50ms, ampl ratio % 27 (9) 183.2 (3.2) 42 (13) 176.3 (3.2) 0.95 0.071
Burst 1, PPF at 10ms, ampl ratio % 21 (6) 187.3 (7.3) 32 (10) 178.5 (4) 0.26 0.31
Burst 1, EPSP3 depr, ampl ratio % 21 (6) 65.1 (2.2) 32 (10) 64.5 (2.2) 0.038 * 0.89
Burst 1, ave amplitude µV 21 (6) 1344 (47) 32 (10) 1357 (48) 0.45 0.86
Burst 2, ave amplitude µV 21 (6) 2334 (93) 32 (10) 2197 (74) 0.075 0.36
Burst 3, ave amplitude µV 21 (6) 2587 (97) 32 (10) 2388 (78) 0.044 * 0.22
Burst 4, ave amplitude µV 21 (6) 2651 (96) 32 (10) 2431 (77) 0.06 0.17
Burst 5, ave amplitude µV 21 (6) 2627 (98) 32 (10) 2372 (74) 0.078 0.1
Burst 6, ave amplitude µV 21 (6) 2568 (100) 32 (10) 2293 (76) 0.096 0.084
Burst 7, ave amplitude µV 21 (6) 2500 (102) 32 (10) 2208 (74) 0.12 0.065
Burst 8, ave amplitude µV 21 (6) 2429 (98) 32 (10) 2140 (76) 0.16 0.061
Burst 9, ave amplitude µV 21 (6) 2372 (101) 31 (10) 2074 (77) 0.2 0.053
Burst 10, ave amplitude µV 21 (6) 2318 (102) 31 (10) 2019 (77) 0.19 0.054
Burst 2-4 ave amplitude vs Burst 1 % 21 (6) 189.3 (5.5) 32 (10) 174.3 (4.1) 0.087 0.084
Burst 8-10 ave amplitude vs Burst 2-4 % 21 (6) 94.8 (1.4) 31 (10) 88.8 (1.4) 0.27 0.017 *
LTP vs PTP, amplitude ratio % 21 (6) 80.6 (1.1) 32 (10) 80.3 (1.1) 0.073 0.88
LTP based on amplitude % 21 (6) 180.8 (3.9) 32 (10) 155.6 (3.8) 0.24 0.0012 **

 

Basal Synaptic Transmission

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Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 34 (11) 3100 (81) 49 (15) 3088 (72) 0.39 0.92

 

Paired Pulse Facilitation

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Variables shown are: PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
PPF at 50ms, ampl ratio % 27 (9) 183.2 (3.2) 42 (13) 176.3 (3.2) 0.95 0.071

 

Theta Burst Stimulation

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Variables shown are: Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Burst 1, PPF at 10ms, ampl ratio % 21 (6) 187.3 (7.3) 32 (10) 178.5 (4) 0.26 0.31
Burst 1, EPSP3 depr, ampl ratio % 21 (6) 65.1 (2.2) 32 (10) 64.5 (2.2) 0.038 * 0.89
Burst 1, ave amplitude µV 21 (6) 1344 (47) 32 (10) 1357 (48) 0.45 0.86
Burst 2, ave amplitude µV 21 (6) 2334 (93) 32 (10) 2197 (74) 0.075 0.36
Burst 3, ave amplitude µV 21 (6) 2587 (97) 32 (10) 2388 (78) 0.044 * 0.22
Burst 4, ave amplitude µV 21 (6) 2651 (96) 32 (10) 2431 (77) 0.06 0.17
Burst 5, ave amplitude µV 21 (6) 2627 (98) 32 (10) 2372 (74) 0.078 0.1
Burst 6, ave amplitude µV 21 (6) 2568 (100) 32 (10) 2293 (76) 0.096 0.084
Burst 7, ave amplitude µV 21 (6) 2500 (102) 32 (10) 2208 (74) 0.12 0.065
Burst 8, ave amplitude µV 21 (6) 2429 (98) 32 (10) 2140 (76) 0.16 0.061
Burst 9, ave amplitude µV 21 (6) 2372 (101) 31 (10) 2074 (77) 0.2 0.053
Burst 10, ave amplitude µV 21 (6) 2318 (102) 31 (10) 2019 (77) 0.19 0.054
Burst 2-4 ave amplitude vs Burst 1 % 21 (6) 189.3 (5.5) 32 (10) 174.3 (4.1) 0.087 0.084
Burst 8-10 ave amplitude vs Burst 2-4 % 21 (6) 94.8 (1.4) 31 (10) 88.8 (1.4) 0.27 0.017 *

 

Long Term Potentiation

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Variables shown are: LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
LTP vs PTP, amplitude ratio % 21 (6) 80.6 (1.1) 32 (10) 80.3 (1.1) 0.073 0.88
LTP based on amplitude % 21 (6) 180.8 (3.9) 32 (10) 155.6 (3.8) 0.24 0.0012 **

Hippocampal brain slices summarised by genotype, followed by a list of the animals from which they were prepared.

View experimental protocols.

 

Hippocampal Slice Electrophysiology Cohort Summary

GenotypeCount
WT11
mutant15

 

Individual Mice

Mouse IDGenotype
wA9a547a8d6WT
wAd59bef0d0WT
wA1facaf1cdWT
wAcbde93eedWT
wA33b6cb06aWT
wA5511bd288WT
wA440832c7fWT
wA9506abcc9WT
wA906f92980WT
wA094979473WT
wA534626477WT
mA95ac89135mutant
mA00b849bb7mutant
mA8aa01b34cmutant
mA4af935a98mutant
mA75e4ff915mutant
mA7a4c7c086mutant
mA9e5650aa6mutant
mA68a3e5064mutant
mA8e9535b39mutant
mA0c2dcee74mutant
mAdf6b34170mutant
mAe7d783867mutant
mAa6cb86c56mutant
mA1072d6a0emutant
mA62482f70emutant

Field EPSP (Maximum)

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA75e4ff915 mutant 1 37A 75e4ff915_slices_1-2-3-4.zip
mA75e4ff915 mutant 2 61A 75e4ff915_slices_1-2-3-4.zip
mA75e4ff915 mutant 4 84B 75e4ff915_slices_1-2-3-4.zip
mA9e5650aa6 mutant 1 57A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 2 52A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 3 46B 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 4 53B 9e5650aa6_slices_1-2-3-4.zip
mA8e9535b39 mutant 1 55A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 2 87A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 3 53B 8e9535b39_slices_1-2-x-3.zip
mAdf6b34170 mutant 1 56A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 2 75A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 3 45B df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 4 52B df6b34170_slices_1-2-3-4.zip
mA1072d6a0e mutant 1 57A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 2 53A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 3 56B 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 4 44B 1072d6a0e_slices_1-2-3-4.zip
mA00b849bb7 mutant 1 37A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 2 44A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 3 45B 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 4 61B 00b849bb7_slices_1-2-3-4.zip
mAa6cb86c56 mutant 1 12A a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 2 15B a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 3 43B a6cb86c56_slices_1-x-2-3.zip
mA62482f70e mutant 1 55A 62482f70e_slices_1-2-x-3.zip
mA62482f70e mutant 2 41A 62482f70e_slices_1-2-x-3.zip
mA62482f70e mutant 3 62B 62482f70e_slices_1-2-x-3.zip
mA8aa01b34c mutant 1 56A 8aa01b34c_slices_1-x-2-3.zip
mA8aa01b34c mutant 2 26B 8aa01b34c_slices_1-x-2-3.zip
mA8aa01b34c mutant 3 84B 8aa01b34c_slices_1-x-2-3.zip
mA68a3e5064 mutant 1 58A 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 2 52A 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 3 58B 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 4 84B 68a3e5064_slices_1-2-3-4.zip
mA7a4c7c086 mutant 1 67A 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 2 42A 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 3 55B 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 4 42B 7a4c7c086_slice_1-2-3-4.zip
mA4af935a98 mutant 1 84A 4af935a98_slice_x-1-2-x.zip
mA4af935a98 mutant 2 46B 4af935a98_slice_x-1-2-x.zip
mAe7d783867 mutant 1 45A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 2 43A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 3 38B e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 4 43B e7d783867_slice_1-2-3-4.zip
mA95ac89135 mutant 1 58A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 2 61A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 3 55B 95ac89135_slice_1-2-3-x.zip
mA0c2dcee74 mutant 1 53A 0c2dcee74_slice_x-1-2-x.zip
wA33b6cb06a WT 2 52A 33b6cb06a_slices_1-2-3-4.zip
wA33b6cb06a WT 3 38B 33b6cb06a_slices_1-2-3-4.zip
wA33b6cb06a WT 4 44B 33b6cb06a_slices_1-2-3-4.zip
wA440832c7f WT 1 15A 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 2 43A 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 3 37B 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 4 44B 440832c7f_slices_1-2-3-4.zip
wA094979473 WT 1 45A 094979473_slices_1-2-3-4.zip
wA094979473 WT 2 53A 094979473_slices_1-2-3-4.zip
wA094979473 WT 3 45B 094979473_slices_1-2-3-4.zip
wA094979473 WT 4 51B 094979473_slices_1-2-3-4.zip
wA9506abcc9 WT 1 45A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 2 54A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 3 47B 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 4 52B 9506abcc9_slices_1-2-3-4.zip
wA5511bd288 WT 1 46A 5511bd288_slices_1-2-3-x.zip
wA5511bd288 WT 2 87A 5511bd288_slices_1-2-3-x.zip
wA5511bd288 WT 3 55B 5511bd288_slices_1-2-3-x.zip
wA534626477 WT 1 67A 534626477_slices_1-2-3-x.zip
wA534626477 WT 2 54A 534626477_slices_1-2-3-x.zip
wA534626477 WT 3 46B 534626477_slices_1-2-3-x.zip
wAcbde93eed WT 1 54A cbde93eed_slices_x-1-2-3.zip
wAcbde93eed WT 2 52B cbde93eed_slices_x-1-2-3.zip
wAcbde93eed WT 3 55B cbde93eed_slices_x-1-2-3.zip
wAd59bef0d0 WT 2 43A d59bef0d0_slices_1-2-3-x.zip
wAd59bef0d0 WT 3 43B d59bef0d0_slices_1-2-3-x.zip
wA906f92980 WT 1 42A 906f92980_slices_x-1-2-x.zip
wA906f92980 WT 2 37B 906f92980_slices_x-1-2-x.zip
wA9a547a8d6 WT 1 46A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 2 42A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 3 84B 9a547a8d6_slice_1-2-x-3.zip
wA1facaf1cd WT 2 61A 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 3 46B 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 4 73B 1facaf1cd_slice_1-2-3-4.zip

Paired Pulse Facilitation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA9e5650aa6 mutant 1 57A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 2 52A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 3 46B 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 4 53B 9e5650aa6_slices_1-2-3-4.zip
mA8e9535b39 mutant 1 55A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 2 87A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 3 53B 8e9535b39_slices_1-2-x-3.zip
mAdf6b34170 mutant 1 56A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 2 75A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 3 45B df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 4 52B df6b34170_slices_1-2-3-4.zip
mA1072d6a0e mutant 1 57A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 2 53A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 3 56B 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 4 44B 1072d6a0e_slices_1-2-3-4.zip
mA00b849bb7 mutant 1 37A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 2 44A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 3 45B 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 4 61B 00b849bb7_slices_1-2-3-4.zip
mAa6cb86c56 mutant 1 12A a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 2 15B a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 3 43B a6cb86c56_slices_1-x-2-3.zip
mA62482f70e mutant 1 55A 62482f70e_slices_1-2-x-3.zip
mA62482f70e mutant 2 41A 62482f70e_slices_1-2-x-3.zip
mA62482f70e mutant 3 62B 62482f70e_slices_1-2-x-3.zip
mA8aa01b34c mutant 1 56A 8aa01b34c_slices_1-x-2-3.zip
mA8aa01b34c mutant 2 26B 8aa01b34c_slices_1-x-2-3.zip
mA8aa01b34c mutant 3 84B 8aa01b34c_slices_1-x-2-3.zip
mA68a3e5064 mutant 1 58A 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 2 52A 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 3 58B 68a3e5064_slices_1-2-3-4.zip
mA68a3e5064 mutant 4 84B 68a3e5064_slices_1-2-3-4.zip
mA7a4c7c086 mutant 1 67A 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 2 42A 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 3 55B 7a4c7c086_slice_1-2-3-4.zip
mA7a4c7c086 mutant 4 42B 7a4c7c086_slice_1-2-3-4.zip
mA4af935a98 mutant 1 84A 4af935a98_slice_x-1-2-x.zip
mA4af935a98 mutant 2 46B 4af935a98_slice_x-1-2-x.zip
mAe7d783867 mutant 1 45A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 2 43A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 3 38B e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 4 43B e7d783867_slice_1-2-3-4.zip
mA95ac89135 mutant 1 58A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 2 61A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 3 55B 95ac89135_slice_1-2-3-x.zip
mA0c2dcee74 mutant 1 53A 0c2dcee74_slice_x-1-2-x.zip
wA094979473 WT 1 45A 094979473_slices_1-2-3-4.zip
wA094979473 WT 2 53A 094979473_slices_1-2-3-4.zip
wA094979473 WT 3 45B 094979473_slices_1-2-3-4.zip
wA094979473 WT 4 51B 094979473_slices_1-2-3-4.zip
wA9506abcc9 WT 1 45A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 2 54A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 3 47B 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 4 52B 9506abcc9_slices_1-2-3-4.zip
wA5511bd288 WT 1 46A 5511bd288_slices_1-2-3-x.zip
wA5511bd288 WT 2 87A 5511bd288_slices_1-2-3-x.zip
wA5511bd288 WT 3 55B 5511bd288_slices_1-2-3-x.zip
wA534626477 WT 1 67A 534626477_slices_1-2-3-x.zip
wA534626477 WT 2 54A 534626477_slices_1-2-3-x.zip
wA534626477 WT 3 46B 534626477_slices_1-2-3-x.zip
wAcbde93eed WT 1 54A cbde93eed_slices_x-1-2-3.zip
wAcbde93eed WT 2 52B cbde93eed_slices_x-1-2-3.zip
wAcbde93eed WT 3 55B cbde93eed_slices_x-1-2-3.zip
wAd59bef0d0 WT 2 43A d59bef0d0_slices_1-2-3-x.zip
wAd59bef0d0 WT 3 43B d59bef0d0_slices_1-2-3-x.zip
wA906f92980 WT 1 42A 906f92980_slices_x-1-2-x.zip
wA906f92980 WT 2 37B 906f92980_slices_x-1-2-x.zip
wA9a547a8d6 WT 1 46A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 2 42A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 3 84B 9a547a8d6_slice_1-2-x-3.zip
wA1facaf1cd WT 2 61A 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 3 46B 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 4 73B 1facaf1cd_slice_1-2-3-4.zip

Long Term Potentiation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA75e4ff915 mutant 1 37A 75e4ff915_slices_1-2-3-4.zip
mA75e4ff915 mutant 2 61A 75e4ff915_slices_1-2-3-4.zip
mA75e4ff915 mutant 4 84B 75e4ff915_slices_1-2-3-4.zip
mA9e5650aa6 mutant 1 57A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 2 52A 9e5650aa6_slices_1-2-3-4.zip
mA9e5650aa6 mutant 3 46B 9e5650aa6_slices_1-2-3-4.zip
mA8e9535b39 mutant 1 55A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 2 87A 8e9535b39_slices_1-2-x-3.zip
mA8e9535b39 mutant 3 53B 8e9535b39_slices_1-2-x-3.zip
mAdf6b34170 mutant 1 56A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 2 75A df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 3 45B df6b34170_slices_1-2-3-4.zip
mAdf6b34170 mutant 4 52B df6b34170_slices_1-2-3-4.zip
mA1072d6a0e mutant 1 57A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 2 53A 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 3 56B 1072d6a0e_slices_1-2-3-4.zip
mA1072d6a0e mutant 4 44B 1072d6a0e_slices_1-2-3-4.zip
mA00b849bb7 mutant 1 37A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 2 44A 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 3 45B 00b849bb7_slices_1-2-3-4.zip
mA00b849bb7 mutant 4 61B 00b849bb7_slices_1-2-3-4.zip
mAa6cb86c56 mutant 1 12A a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 2 15B a6cb86c56_slices_1-x-2-3.zip
mAa6cb86c56 mutant 3 43B a6cb86c56_slices_1-x-2-3.zip
mAe7d783867 mutant 1 45A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 2 43A e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 3 38B e7d783867_slice_1-2-3-4.zip
mAe7d783867 mutant 4 43B e7d783867_slice_1-2-3-4.zip
mA95ac89135 mutant 1 58A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 2 61A 95ac89135_slice_1-2-3-x.zip
mA95ac89135 mutant 3 55B 95ac89135_slice_1-2-3-x.zip
mA0c2dcee74 mutant 1 53A 0c2dcee74_slice_x-1-2-x.zip
wA33b6cb06a WT 2 52A 33b6cb06a_slices_1-2-3-4.zip
wA33b6cb06a WT 3 38B 33b6cb06a_slices_1-2-3-4.zip
wA33b6cb06a WT 4 44B 33b6cb06a_slices_1-2-3-4.zip
wA440832c7f WT 1 15A 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 2 43A 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 3 37B 440832c7f_slices_1-2-3-4.zip
wA440832c7f WT 4 44B 440832c7f_slices_1-2-3-4.zip
wA094979473 WT 1 45A 094979473_slices_1-2-3-4.zip
wA094979473 WT 2 53A 094979473_slices_1-2-3-4.zip
wA094979473 WT 3 45B 094979473_slices_1-2-3-4.zip
wA094979473 WT 4 51B 094979473_slices_1-2-3-4.zip
wA9506abcc9 WT 1 45A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 2 54A 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 3 47B 9506abcc9_slices_1-2-3-4.zip
wA9506abcc9 WT 4 52B 9506abcc9_slices_1-2-3-4.zip
wA9a547a8d6 WT 1 46A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 2 42A 9a547a8d6_slice_1-2-x-3.zip
wA9a547a8d6 WT 3 84B 9a547a8d6_slice_1-2-x-3.zip
wA1facaf1cd WT 2 61A 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 3 46B 1facaf1cd_slice_1-2-3-4.zip
wA1facaf1cd WT 4 73B 1facaf1cd_slice_1-2-3-4.zip

Data Files

File NameSizeChecksum (SHA256)
7a4c7c086_slice_1-2-3-4.zip44907843343c648f03b5d09bbb9b95a3341a480a0e99cf81dec9b3661af53d699955642f
68a3e5064_slices_1-2-3-4.zip35688439587ee4d3fc55fbdf8e872185997acea1bcec1965721f44d35d6a1735deae5e3c
906f92980_slices_x-1-2-x.zip42617868f271aaf351ff286232a4ab3af16fee89e5695a99d03e7320087bde1c7374e34f
440832c7f_slices_1-2-3-4.zip3145994271e85ab12a870a63692da6f5c863d0362b7bc23f5831fb85b024b9d69bb6a1af
4af935a98_slice_x-1-2-x.zip389374026142848e29c2e292e1caf020f08b86ae7a2ac7f0fb2f82bb3b63c36722b447eb
cbde93eed_slices_x-1-2-3.zip36269169b380378572267f73a67f46221d32fe11c9bc9dab085be983aa837fb9b34a261f
0c2dcee74_slice_x-1-2-x.zip2997712101f578e7cd45882c1a1585b4db67a523432bbb885a06f5357f15772a74f7cbe7
094979473_slices_1-2-3-4.zip435582131184c06b89cb1d2404feef7d06c21d802484d9607eff959223e984ed7c2ccc74
9506abcc9_slices_1-2-3-4.zip43489092b73ff86824a26bb7e15720350ce7cb6891b251999dc9b7b0926fa07974380c09
1facaf1cd_slice_1-2-3-4.zip550319632a5ec5bb7fbd37a59ceb6bf0ab1ca2eb339a80cb0149d37d83719909a1c98360
9a547a8d6_slice_1-2-x-3.zip44902606531a9757451725448060fed2def10b999db6f5e80bfa0b8b52f62f3829bba96a
e7d783867_slice_1-2-3-4.zip453245768d8a23ecbda8b2192ee66ecf2b0b9d5377fd76c8d842b6d9af59fac2f779f4ee
9e5650aa6_slices_1-2-3-4.zip367859991202c2e71256a78daa5316588107aa84a1752e7328327c98e30d76c4f1ede052
a6cb86c56_slices_1-x-2-3.zip31606582c4f5b7efe80aec92d743d0e1acb43e1f30a5acdd1fc1e91607e6443630c2ba16
534626477_slices_1-2-3-x.zip51689641180c3693b1e790b001ac64237d633b0dfd3ee2e3b3fbe9748a564d6afae36490
75e4ff915_slices_1-2-3-4.zip414550128e0f797be47b482f9ed3b1794648f58ce2fe0e051b74eb331387458dc9a800d2
1072d6a0e_slices_1-2-3-4.zip41486690645886b4a23a8d3577739db7c8b2f27a97fc4db7727999e7e690706125526c93
df6b34170_slices_1-2-3-4.zip3239373889a68ea754375af19dc94141335957573572996f3301b1ceb122f5d80973874d
00b849bb7_slices_1-2-3-4.zip63040250582c31290d0f2779ecbe649d4625cea24e9804adedbf32cebbc4c8091e9b178b
33b6cb06a_slices_1-2-3-4.zip4611397723bdeb1640572708a1089c9f531f12aa34fbe9424ad77fedd082eb574f72c417
5511bd288_slices_1-2-3-x.zip43989115bc6227fe2304cc693acc2edf651120522d1418059c1a04610e1f386c4d482cd3
d59bef0d0_slices_1-2-3-x.zip317192851dfcad89f4417df19ce63c68ca0aa13aaaea9f55240f854ac4c23025573eef3a
8aa01b34c_slices_1-x-2-3.zip32926169c15e847860564e7190a8571b3a5cf61739e41510dd73b9a6659ad6045b46d20a
62482f70e_slices_1-2-x-3.zip27719293a1d8512a86956760d18994e49994f19e3f9ea8daa62b3e06d37a573811382ecc
95ac89135_slice_1-2-3-x.zip36550604ce6d9e05135a6f1a21f1d186cc29b7f72b67009a350a8492ebcb06edd890905f
8e9535b39_slices_1-2-x-3.zip32697563275d3c016fbdf2f8992f6fe82005c4708ea30bd0579ad1f85fa1240932b8bfeb
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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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