G2C::Electrophysiology

H-Ras knock-out mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 18 electrophysiology variables

Mutant slices showed medium overall electrophysiological difference from wildtype slices, with three of nine variables significantly impacted in these mutant slices. In the theta burst stimulation experiment, three electrophysiological variables of five were significantly impacted in mutants. Basal synaptic transmission, paired pulse facilitation and long term potentiation experiments were unaffected. Note that in the theta burst analysis, the tenth burst is analysed as representative of individual burst amplitude. Definitions of variables may be found below.

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The G2CMine data warehouse provides slice group summaries and individual mouse observations from the H-Ras knock-out line phenotyping.

 

Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude. PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio. Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4. LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 30 (10) 3036 (72) 40 (12) 3160 (78) 0.15 0.33
PPF at 50ms, ampl ratio % 30 (10) 170.8 (3.1) 40 (12) 166.4 (2.5) 0.95 0.16
Burst 1, PPF at 10ms, ampl ratio % 16 (5) 177.6 (8.7) 25 (7) 159.1 (3.4) 0.44 0.048 *
Burst 1, EPSP3 depr, ampl ratio % 16 (5) 64.1 (4) 25 (7) 73.4 (2.4) 0.63 0.045 *
Burst 1, ave amplitude µV 16 (5) 1296 (43) 25 (7) 1349 (42) 0.083 0.52
Burst 2, ave amplitude µV 16 (5) 2118 (100) 25 (7) 2111 (54) 0.61 0.94
Burst 3, ave amplitude µV 16 (5) 2307 (98) 25 (7) 2275 (57) 0.6 0.75
Burst 4, ave amplitude µV 16 (5) 2350 (100) 25 (7) 2293 (57) 0.6 0.58
Burst 5, ave amplitude µV 16 (5) 2284 (91) 25 (7) 2240 (56) 0.69 0.64
Burst 6, ave amplitude µV 16 (5) 2221 (92) 25 (7) 2182 (55) 0.63 0.68
Burst 7, ave amplitude µV 16 (5) 2143 (85) 25 (7) 2116 (54) 0.61 0.77
Burst 8, ave amplitude µV 16 (5) 2076 (80) 25 (7) 2058 (51) 0.6 0.83
Burst 9, ave amplitude µV 16 (5) 2039 (81) 25 (7) 2009 (50) 0.65 0.71
Burst 10, ave amplitude µV 16 (5) 1992 (77) 25 (7) 1956 (46) 0.58 0.66
Burst 2-4 ave amplitude vs Burst 1 % 16 (5) 173.5 (3.7) 25 (7) 165.6 (2.9) 0.98 0.017 *
Burst 8-10 ave amplitude vs Burst 2-4 % 16 (5) 90.6 (1.4) 25 (7) 90.3 (1.4) 1 0.73
LTP vs PTP, amplitude ratio % 16 (5) 80.3 (1.2) 25 (7) 81.8 (1) 0.27 0.43
LTP based on amplitude % 16 (5) 162.4 (5.3) 25 (7) 155.9 (4.4) 0.75 0.29

 

Basal Synaptic Transmission

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Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 30 (10) 3036 (72) 40 (12) 3160 (78) 0.15 0.33

 

Paired Pulse Facilitation

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Variables shown are: PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
PPF at 50ms, ampl ratio % 30 (10) 170.8 (3.1) 40 (12) 166.4 (2.5) 0.95 0.16

 

Theta Burst Stimulation

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Variables shown are: Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Burst 1, PPF at 10ms, ampl ratio % 16 (5) 177.6 (8.7) 25 (7) 159.1 (3.4) 0.44 0.048 *
Burst 1, EPSP3 depr, ampl ratio % 16 (5) 64.1 (4) 25 (7) 73.4 (2.4) 0.63 0.045 *
Burst 1, ave amplitude µV 16 (5) 1296 (43) 25 (7) 1349 (42) 0.083 0.52
Burst 2, ave amplitude µV 16 (5) 2118 (100) 25 (7) 2111 (54) 0.61 0.94
Burst 3, ave amplitude µV 16 (5) 2307 (98) 25 (7) 2275 (57) 0.6 0.75
Burst 4, ave amplitude µV 16 (5) 2350 (100) 25 (7) 2293 (57) 0.6 0.58
Burst 5, ave amplitude µV 16 (5) 2284 (91) 25 (7) 2240 (56) 0.69 0.64
Burst 6, ave amplitude µV 16 (5) 2221 (92) 25 (7) 2182 (55) 0.63 0.68
Burst 7, ave amplitude µV 16 (5) 2143 (85) 25 (7) 2116 (54) 0.61 0.77
Burst 8, ave amplitude µV 16 (5) 2076 (80) 25 (7) 2058 (51) 0.6 0.83
Burst 9, ave amplitude µV 16 (5) 2039 (81) 25 (7) 2009 (50) 0.65 0.71
Burst 10, ave amplitude µV 16 (5) 1992 (77) 25 (7) 1956 (46) 0.58 0.66
Burst 2-4 ave amplitude vs Burst 1 % 16 (5) 173.5 (3.7) 25 (7) 165.6 (2.9) 0.98 0.017 *
Burst 8-10 ave amplitude vs Burst 2-4 % 16 (5) 90.6 (1.4) 25 (7) 90.3 (1.4) 1 0.73

 

Long Term Potentiation

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Variables shown are: LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
LTP vs PTP, amplitude ratio % 16 (5) 80.3 (1.2) 25 (7) 81.8 (1) 0.27 0.43
LTP based on amplitude % 16 (5) 162.4 (5.3) 25 (7) 155.9 (4.4) 0.75 0.29

Hippocampal brain slices summarised by genotype, followed by a list of the animals from which they were prepared.

View experimental protocols.

 

Hippocampal Slice Electrophysiology Cohort Summary

GenotypeCount
WT10
mutant12

 

Individual Mice

Mouse IDGenotype
wAa9af1eab1WT
wB7be0594d5WT
wA12eba9fc4WT
wAb1043f4fdWT
wAc0c51c838WT
wA83d7728cdWT
wAad9b1a34bWT
wAffdc74c36WT
wA628204902WT
wA42ff811b3WT
mA0547dbaffmutant
mA7be0594d5mutant
mA56bd72ab0mutant
mA16f57ad0amutant
mAd6f73473fmutant
mAf2192c01emutant
mAaec500fccmutant
mA0bb390a67mutant
mA3dc89ff47mutant
mAb1fdd7859mutant
mA82453bddemutant
mAe9791a9d5mutant

Field EPSP (Maximum)

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA3dc89ff47 mutant 1 57A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 2 62A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 3 28B 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 4 43B 3dc89ff47_slices_1-2-3-4.zip
mAaec500fcc mutant 1 12A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 2 62A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 3 12B aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 4 54B aec500fcc_slices_1-2-3-4.zip
mAe9791a9d5 mutant 1 57A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 2 54A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 3 24B e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 4 31B e9791a9d5_slices_1-2-3-4.zip
mA82453bdde mutant 1 45A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 2 61A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 3 47B 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 4 71B 82453bdde_slices_1-2-3-4.zip
mA56bd72ab0 mutant 1 57A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 2 54A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 3 46B 56bd72ab0_slices_1-2-3-x.zip
mA0bb390a67 mutant 1 47A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 2 12A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 3 24B 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 4 31B 0bb390a67_slices_1-2-3-4.zip
mA16f57ad0a mutant 1 46A 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 2 52A 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 3 57B 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 4 44B 16f57ad0a_slices_1-2-3-4.zip
mA0547dbaff mutant 1 47A 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 2 42A 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 3 38B 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 4 87B 0547dbaff_slice_1-2-3-4.zip
mAd6f73473f mutant 1 45A d6f73473f_slice_1-2-3-x.zip
mAd6f73473f mutant 2 42A d6f73473f_slice_1-2-3-x.zip
mAd6f73473f mutant 3 12B d6f73473f_slice_1-2-3-x.zip
mAf2192c01e mutant 1 37B f2192c01e_slice__x-x-1-x.zip
mAb1fdd7859 mutant 1 43A b1fdd7859_slice_x-1-2-3.zip
mAb1fdd7859 mutant 2 46B b1fdd7859_slice_x-1-2-3.zip
mAb1fdd7859 mutant 3 53B b1fdd7859_slice_x-1-2-3.zip
mA7be0594d5 mutant 1 61A 7be0594d5_slices_x-1-2-x.zip
mA7be0594d5 mutant 2 12B 7be0594d5_slices_x-1-2-x.zip
wAa9af1eab1 WT 1 57A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 2 53A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 3 56B a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 4 62B a9af1eab1_slices_1-2-3-4.zip
wAad9b1a34b WT 1 46A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 2 61A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 3 38B ad9b1a34b_slices_1-2-3-4.zip
wAc0c51c838 WT 2 42A c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 3 46B c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 4 84B c0c51c838_slices_1-2-3-4.zip
wA12eba9fc4 WT 1 84A 12eba9fc4_slices_x-1-2-3.zip
wA12eba9fc4 WT 3 87B 12eba9fc4_slices_x-1-2-3.zip
wA628204902 WT 1 61A 628204902_slices_x-1-2-3.zip
wA628204902 WT 3 52B 628204902_slices_x-1-2-3.zip
wAffdc74c36 WT 1 28A ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 2 52A ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 3 67B ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 4 43B ffdc74c36_slices_1-2-3-4.zip
wAb1043f4fd WT 1 56A b1043f4fd_slice_1-2-3-4.zip
wAb1043f4fd WT 2 87A b1043f4fd_slice_1-2-3-4.zip
wAb1043f4fd WT 3 58B b1043f4fd_slice_1-2-3-4.zip
wA83d7728cd WT 1 46A 83d7728cd_slice_1-2-x-x.zip
wA83d7728cd WT 2 54A 83d7728cd_slice_1-2-x-x.zip
wA42ff811b3 WT 2 43A 42ff811b3_slice_1-2-3-4.zip
wA42ff811b3 WT 3 37B 42ff811b3_slice_1-2-3-4.zip
wA42ff811b3 WT 4 43B 42ff811b3_slice_1-2-3-4.zip
wB7be0594d5 WT 3 12A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 4 52A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 5 46B 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 6 43B 7be0594d5_slices_3-4-5-6.zip

Paired Pulse Facilitation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA3dc89ff47 mutant 1 57A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 2 62A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 3 28B 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 4 43B 3dc89ff47_slices_1-2-3-4.zip
mAaec500fcc mutant 1 12A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 2 62A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 3 12B aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 4 54B aec500fcc_slices_1-2-3-4.zip
mAe9791a9d5 mutant 1 57A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 2 54A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 3 24B e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 4 31B e9791a9d5_slices_1-2-3-4.zip
mA82453bdde mutant 1 45A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 2 61A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 3 47B 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 4 71B 82453bdde_slices_1-2-3-4.zip
mA56bd72ab0 mutant 1 57A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 2 54A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 3 46B 56bd72ab0_slices_1-2-3-x.zip
mA0bb390a67 mutant 1 47A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 2 12A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 3 24B 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 4 31B 0bb390a67_slices_1-2-3-4.zip
mA16f57ad0a mutant 1 46A 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 2 52A 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 3 57B 16f57ad0a_slices_1-2-3-4.zip
mA16f57ad0a mutant 4 44B 16f57ad0a_slices_1-2-3-4.zip
mA0547dbaff mutant 1 47A 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 2 42A 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 3 38B 0547dbaff_slice_1-2-3-4.zip
mA0547dbaff mutant 4 87B 0547dbaff_slice_1-2-3-4.zip
mAd6f73473f mutant 1 45A d6f73473f_slice_1-2-3-x.zip
mAd6f73473f mutant 2 42A d6f73473f_slice_1-2-3-x.zip
mAd6f73473f mutant 3 12B d6f73473f_slice_1-2-3-x.zip
mAf2192c01e mutant 1 37B f2192c01e_slice__x-x-1-x.zip
mAb1fdd7859 mutant 1 43A b1fdd7859_slice_x-1-2-3.zip
mAb1fdd7859 mutant 2 46B b1fdd7859_slice_x-1-2-3.zip
mAb1fdd7859 mutant 3 53B b1fdd7859_slice_x-1-2-3.zip
mA7be0594d5 mutant 1 61A 7be0594d5_slices_x-1-2-x.zip
mA7be0594d5 mutant 2 12B 7be0594d5_slices_x-1-2-x.zip
wAa9af1eab1 WT 1 57A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 2 53A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 3 56B a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 4 62B a9af1eab1_slices_1-2-3-4.zip
wAad9b1a34b WT 1 46A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 2 61A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 3 38B ad9b1a34b_slices_1-2-3-4.zip
wAc0c51c838 WT 2 42A c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 3 46B c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 4 84B c0c51c838_slices_1-2-3-4.zip
wA12eba9fc4 WT 1 84A 12eba9fc4_slices_x-1-2-3.zip
wA12eba9fc4 WT 3 87B 12eba9fc4_slices_x-1-2-3.zip
wA628204902 WT 1 61A 628204902_slices_x-1-2-3.zip
wA628204902 WT 3 52B 628204902_slices_x-1-2-3.zip
wAffdc74c36 WT 1 28A ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 2 52A ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 3 67B ffdc74c36_slices_1-2-3-4.zip
wAffdc74c36 WT 4 43B ffdc74c36_slices_1-2-3-4.zip
wAb1043f4fd WT 1 56A b1043f4fd_slice_1-2-3-4.zip
wAb1043f4fd WT 2 87A b1043f4fd_slice_1-2-3-4.zip
wAb1043f4fd WT 3 58B b1043f4fd_slice_1-2-3-4.zip
wA83d7728cd WT 1 46A 83d7728cd_slice_1-2-x-x.zip
wA83d7728cd WT 2 54A 83d7728cd_slice_1-2-x-x.zip
wA42ff811b3 WT 2 43A 42ff811b3_slice_1-2-3-4.zip
wA42ff811b3 WT 3 37B 42ff811b3_slice_1-2-3-4.zip
wA42ff811b3 WT 4 43B 42ff811b3_slice_1-2-3-4.zip
wB7be0594d5 WT 3 12A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 4 52A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 5 46B 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 6 43B 7be0594d5_slices_3-4-5-6.zip

Long Term Potentiation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA3dc89ff47 mutant 1 57A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 2 62A 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 3 28B 3dc89ff47_slices_1-2-3-4.zip
mA3dc89ff47 mutant 4 43B 3dc89ff47_slices_1-2-3-4.zip
mAaec500fcc mutant 1 12A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 2 62A aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 3 12B aec500fcc_slices_1-2-3-4.zip
mAaec500fcc mutant 4 54B aec500fcc_slices_1-2-3-4.zip
mAe9791a9d5 mutant 1 57A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 2 54A e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 3 24B e9791a9d5_slices_1-2-3-4.zip
mAe9791a9d5 mutant 4 31B e9791a9d5_slices_1-2-3-4.zip
mA82453bdde mutant 1 45A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 2 61A 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 3 47B 82453bdde_slices_1-2-3-4.zip
mA82453bdde mutant 4 71B 82453bdde_slices_1-2-3-4.zip
mA56bd72ab0 mutant 1 57A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 2 54A 56bd72ab0_slices_1-2-3-x.zip
mA56bd72ab0 mutant 3 46B 56bd72ab0_slices_1-2-3-x.zip
mA0bb390a67 mutant 1 47A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 2 12A 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 3 24B 0bb390a67_slices_1-2-3-4.zip
mA0bb390a67 mutant 4 31B 0bb390a67_slices_1-2-3-4.zip
mA7be0594d5 mutant 1 61A 7be0594d5_slices_x-1-2-x.zip
mA7be0594d5 mutant 2 12B 7be0594d5_slices_x-1-2-x.zip
wAa9af1eab1 WT 1 57A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 2 53A a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 3 56B a9af1eab1_slices_1-2-3-4.zip
wAa9af1eab1 WT 4 62B a9af1eab1_slices_1-2-3-4.zip
wAad9b1a34b WT 1 46A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 2 61A ad9b1a34b_slices_1-2-3-4.zip
wAad9b1a34b WT 3 38B ad9b1a34b_slices_1-2-3-4.zip
wAc0c51c838 WT 2 42A c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 3 46B c0c51c838_slices_1-2-3-4.zip
wAc0c51c838 WT 4 84B c0c51c838_slices_1-2-3-4.zip
wA12eba9fc4 WT 1 84A 12eba9fc4_slices_x-1-2-3.zip
wA12eba9fc4 WT 3 87B 12eba9fc4_slices_x-1-2-3.zip
wB7be0594d5 WT 3 12A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 4 52A 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 5 46B 7be0594d5_slices_3-4-5-6.zip
wB7be0594d5 WT 6 43B 7be0594d5_slices_3-4-5-6.zip

Data Files

File NameSizeChecksum (SHA256)
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0547dbaff_slice_1-2-3-4.zip3590012959f4baa40818a07787eb9ef9b7a6a0a9807d1a92884707df614f582a020df4cd
0bb390a67_slices_1-2-3-4.zip36540989949dc11017de1c39bb396420f9ed5df0c1cdc0349d96c0800a8e15d8194a5421
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3dc89ff47_slices_1-2-3-4.zip35311899a12e59cb99b8af9cc2ee4106719747a6df24a2f816722352ad0c7fa59f420baa
b1fdd7859_slice_x-1-2-3.zip3553418753e4a3f7059cfd9c873d38c037cf32f727539cffcdd9b105f0b83db377c9f23b
56bd72ab0_slices_1-2-3-x.zip378050887a1d76159da25b69533b32ea116085257b0688f5a99d50e983d930d5e95a9651
a9af1eab1_slices_1-2-3-4.zip42189096a7404ae7a5253c85bc5e9950396abe4c86eae1fcef9d7cb190052037b3014288
b1043f4fd_slice_1-2-3-4.zip34873562b9573b8b7555abc20da5f441e84331dee6b7b9467fc198a46749ecd555c34610
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ad9b1a34b_slices_1-2-3-4.zip43651884dc3bb26067e69d4bddd60eb82ad8adffb2c7cfb8a9d3db66f138ee6869636648
12eba9fc4_slices_x-1-2-3.zip33032550b12d144c526b96694d4a2a94b64a82652bce67d47d9060e348494155cd8eb384
628204902_slices_x-1-2-3.zip45019431b83c45c7471c456efa1286eeab94e9573b899a119f3620a937a35dbddd5a6aa7
e9791a9d5_slices_1-2-3-4.zip35522549e531eb41fff260daa6fa8219411e1a6da085e9d552d200ef438548a88e3364c5
f2192c01e_slice__x-x-1-x.zip363800433d00e5d0880cdb79d0a5ae82a535f3753b9f385977122a553f2141ff267ffd80
16f57ad0a_slices_1-2-3-4.zip4680910681749e171a28a0d6d8fcc141afa078c04e35f8c3d63cf0af1e4fc91f63d72cd7
7be0594d5_slices_x-1-2-x.zip293491440cb8ae193ebac0a59487be45c5f9bbcc62b3abefe7bb752c0eb07c52c8bc6910
aec500fcc_slices_1-2-3-4.zip41844930112df8d87d7f781664cc0ea6c0cc94ea0fdc3ea3e98b04d7c278f518d719fd44
82453bdde_slices_1-2-3-4.zip32707125993835d7b0d2c7f78da5a6b85225900836d79c2f1058a473f90dca6d0ef224cd
83d7728cd_slice_1-2-x-x.zip54289671773e98ca7d1e0dfcff9e577ae409e208a5e77d5ba5f846d90c708326b8fe663e
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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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