G2C::Electrophysiology

SynGAP knock-out mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 18 electrophysiology variables

Mutant slices showed medium overall electrophysiological difference from wildtype slices, with two of nine variables significantly impacted by this mutation. In the long term potentiation experiment, two electrophysiological variables of two were significantly impacted in mutants. Basal synaptic transmission, paired pulse facilitation and theta burst stimulation experiments were unaffected. Note that in the theta burst analysis, the tenth burst is analysed as representative of individual burst amplitude. Definitions of variables may be found below.

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The G2CMine data warehouse provides slice group summaries and individual mouse observations from the SynGAP knock-out line phenotyping.

 

Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude. PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio. Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4. LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 41 (14) 3034 (101) 52 (18) 3176 (98) 0.11 0.39
PPF at 50ms, ampl ratio % 18 (6) 180.7 (4.8) 22 (7) 180.8 (4.3) 0.081 0.99
Burst 1, PPF at 10ms, ampl ratio % 34 (11) 185.2 (4.6) 32 (10) 194.7 (5.2) 0.16 0.23
Burst 1, EPSP3 depr, ampl ratio % 34 (11) 64.7 (2.1) 32 (10) 62.7 (1.9) 0.43 0.5
Burst 1, ave amplitude µV 34 (11) 1348 (50) 32 (10) 1389 (56) 0.045 * 0.65
Burst 2, ave amplitude µV 34 (11) 2228 (81) 32 (10) 2303 (101) 0.2 0.6
Burst 3, ave amplitude µV 34 (11) 2458 (85) 32 (10) 2491 (105) 0.24 0.83
Burst 4, ave amplitude µV 34 (11) 2504 (80) 32 (10) 2523 (101) 0.27 0.9
Burst 5, ave amplitude µV 34 (11) 2449 (76) 32 (10) 2486 (100) 0.29 0.79
Burst 6, ave amplitude µV 34 (11) 2385 (72) 32 (10) 2406 (100) 0.33 0.87
Burst 7, ave amplitude µV 34 (11) 2297 (72) 32 (10) 2318 (96) 0.31 0.87
Burst 8, ave amplitude µV 34 (11) 2242 (67) 32 (10) 2230 (94) 0.36 0.92
Burst 9, ave amplitude µV 34 (11) 2175 (68) 32 (10) 2152 (94) 0.44 0.85
Burst 10, ave amplitude µV 34 (11) 2121 (66) 32 (10) 2086 (91) 0.33 0.77
Burst 2-4 ave amplitude vs Burst 1 % 34 (11) 179.6 (4.6) 32 (10) 176.6 (4.1) 0.031 * 0.7
Burst 8-10 ave amplitude vs Burst 2-4 % 34 (11) 91.8 (1.1) 32 (10) 88.4 (1.2) 0.2 0.069
LTP vs PTP, amplitude ratio % 34 (11) 80.1 (1.1) 32 (10) 75.6 (0.6) 0.34 0.0022 **
LTP based on amplitude % 34 (11) 170.5 (4) 32 (10) 147.8 (3.2) 0.96 1.1e-05 ***

 

Basal Synaptic Transmission

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Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 41 (14) 3034 (101) 52 (18) 3176 (98) 0.11 0.39

 

Paired Pulse Facilitation

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Variables shown are: PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
PPF at 50ms, ampl ratio % 18 (6) 180.7 (4.8) 22 (7) 180.8 (4.3) 0.081 0.99

 

Theta Burst Stimulation

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Variables shown are: Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Burst 1, PPF at 10ms, ampl ratio % 34 (11) 185.2 (4.6) 32 (10) 194.7 (5.2) 0.16 0.23
Burst 1, EPSP3 depr, ampl ratio % 34 (11) 64.7 (2.1) 32 (10) 62.7 (1.9) 0.43 0.5
Burst 1, ave amplitude µV 34 (11) 1348 (50) 32 (10) 1389 (56) 0.045 * 0.65
Burst 2, ave amplitude µV 34 (11) 2228 (81) 32 (10) 2303 (101) 0.2 0.6
Burst 3, ave amplitude µV 34 (11) 2458 (85) 32 (10) 2491 (105) 0.24 0.83
Burst 4, ave amplitude µV 34 (11) 2504 (80) 32 (10) 2523 (101) 0.27 0.9
Burst 5, ave amplitude µV 34 (11) 2449 (76) 32 (10) 2486 (100) 0.29 0.79
Burst 6, ave amplitude µV 34 (11) 2385 (72) 32 (10) 2406 (100) 0.33 0.87
Burst 7, ave amplitude µV 34 (11) 2297 (72) 32 (10) 2318 (96) 0.31 0.87
Burst 8, ave amplitude µV 34 (11) 2242 (67) 32 (10) 2230 (94) 0.36 0.92
Burst 9, ave amplitude µV 34 (11) 2175 (68) 32 (10) 2152 (94) 0.44 0.85
Burst 10, ave amplitude µV 34 (11) 2121 (66) 32 (10) 2086 (91) 0.33 0.77
Burst 2-4 ave amplitude vs Burst 1 % 34 (11) 179.6 (4.6) 32 (10) 176.6 (4.1) 0.031 * 0.7
Burst 8-10 ave amplitude vs Burst 2-4 % 34 (11) 91.8 (1.1) 32 (10) 88.4 (1.2) 0.2 0.069

 

Long Term Potentiation

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Variables shown are: LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
LTP vs PTP, amplitude ratio % 34 (11) 80.1 (1.1) 32 (10) 75.6 (0.6) 0.34 0.0022 **
LTP based on amplitude % 34 (11) 170.5 (4) 32 (10) 147.8 (3.2) 0.96 1.1e-05 ***

Hippocampal brain slices summarised by genotype, followed by a list of the animals from which they were prepared.

View experimental protocols.

 

Hippocampal Slice Electrophysiology Cohort Summary

GenotypeCount
WT14
mutant19

 

Individual Mice

Mouse IDGenotype
wA68f02fa73WT
wAd64812350WT
wAe8382bc11WT
wAef1f233e7WT
wAd3d31660fWT
wA4a6fe1848WT
wA5a4e865caWT
wA41554e619WT
wA8a7fa98bcWT
wAd5b9e0942WT
wA983f61187WT
wAf87e2f168WT
wAc83faf364WT
wA6725b26d7WT
mA253bc8fc0mutant
mAc7876080dmutant
mA7379e2114mutant
mAb5bdcf42cmutant
mA9aaaca937mutant
mAd9952ae17mutant
mAdcb8a65dcmutant
mA1b3ebd427mutant
mAbad7e5811mutant
mA1c1ef6008mutant
mA6b79cc872mutant
mA48b5fbaebmutant
mA786a52f10mutant
mA9fa0f988emutant
mA2c0db83c3mutant
mAd7d9a6cd5mutant
mA1a637500fmutant
mAbd6450afbmutant
mA40b721c83mutant

Field EPSP (Maximum)

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA2c0db83c3 mutant 2 12A 2c0db83c3_slices_1-2-3.zip
mA2c0db83c3 mutant 3 12B 2c0db83c3_slices_1-2-3.zip
mA2c0db83c3 mutant 4 45A 2c0db83c3_slices_x-4-5.zip
mA2c0db83c3 mutant 5 38B 2c0db83c3_slices_x-4-5.zip
mA9aaaca937 mutant 1 45A 9aaaca937_slices_1-2-3.zip
mA9aaaca937 mutant 2 42A 9aaaca937_slices_1-2-3.zip
mAbad7e5811 mutant 1 43A bad7e5811_slices_1-2-3.zip
mAbd6450afb mutant 1 47A bd6450afb_slices_1-2-3.zip
mAbd6450afb mutant 2 42A bd6450afb_slices_1-2-3.zip
mAbd6450afb mutant 3 12B bd6450afb_slices_1-2-3.zip
mA6b79cc872 mutant 1 45A 6b79cc872_slices_1-2-3.zip
mA6b79cc872 mutant 2 52A 6b79cc872_slices_1-2-3.zip
mA6b79cc872 mutant 3 53B 6b79cc872_slices_1-2-3.zip
mA7379e2114 mutant 1 47A 7379e2114_slices_1-2-3.zip
mA7379e2114 mutant 3 62B 7379e2114_slices_1-2-3.zip
mA1c1ef6008 mutant 1 42A 1c1ef6008_slices_1-2-3.zip
mA1c1ef6008 mutant 3 12B 1c1ef6008_slices_1-2-3.zip
mA48b5fbaeb mutant 1 53A 48b5fbaeb_slices_x-1-2-3.zip
mA48b5fbaeb mutant 2 47B 48b5fbaeb_slices_x-1-2-3.zip
mA48b5fbaeb mutant 3 43B 48b5fbaeb_slices_x-1-2-3.zip
mAdcb8a65dc mutant 1 55A dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 2 44A dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 3 28B dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 4 61B dcb8a65dc_slices_1-2-3-4.zip
mAc7876080d mutant 1 47A c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 2 53A c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 3 37B c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 4 44B c7876080d_slices_1-2-3-4.zip
mA1a637500f mutant 1 12A 1a637500f_slices_1-2-3-4.zip
mA1a637500f mutant 3 47B 1a637500f_slices_1-2-3-4.zip
mA1a637500f mutant 4 53B 1a637500f_slices_1-2-3-4.zip
mA786a52f10 mutant 1 37A 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 2 53A 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 3 37B 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 4 44B 786a52f10_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 1 45A d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 3 58B d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 4 41B d7d9a6cd5_slices_1-2-3-4.zip
mA253bc8fc0 mutant 2 61A 253bc8fc0_slices_1-2-x-3.zip
mA253bc8fc0 mutant 3 43B 253bc8fc0_slices_1-2-x-3.zip
mAb5bdcf42c mutant 1 62B b5bdcf42c_slices_x-x-x-1.zip
mA9fa0f988e mutant 1 58A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 2 42A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 3 57B 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 4 53B 9fa0f988e_slices_1-2-3-4.zip
mA40b721c83 mutant 1 86A 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 2 55B 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 3 52B 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 5 61A 40b721c83_slices_4-5-6-7.zip
mA40b721c83 mutant 6 46B 40b721c83_slices_4-5-6-7.zip
mAd9952ae17 mutant 1 15A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 2 41A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 3 15B d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 4 41B d9952ae17_slices_1-2-3-4.zip
mA1b3ebd427 mutant 2 43A 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 3 46B 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 4 52B 1b3ebd427_slices_1-2-3-4.zip
wA4a6fe1848 WT 1 42A 4a6fe1848_slices_1-2-3.zip
wA4a6fe1848 WT 2 26A 4a6fe1848_slices_1-2-3.zip
wA4a6fe1848 WT 3 24B 4a6fe1848_slices_1-2-3.zip
wAc83faf364 WT 1 57A c83faf364_slices_1-2-3.zip
wAc83faf364 WT 2 52A c83faf364_slices_1-2-3.zip
wAc83faf364 WT 3 61B c83faf364_slices_1-2-3.zip
wAe8382bc11 WT 1 47A e8382bc11_slices_1-2-3.zip
wAe8382bc11 WT 2 43A e8382bc11_slices_1-2-3.zip
wAe8382bc11 WT 3 42B e8382bc11_slices_1-2-3.zip
wA68f02fa73 WT 1 38A 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 2 53A 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 3 46B 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 4 53B 68f02fa73_slices_1-2-3-4.zip
wA983f61187 WT 1 46A 983f61187_slices_1-2-3-x.zip
wA983f61187 WT 2 42A 983f61187_slices_1-2-3-x.zip
wA983f61187 WT 3 57B 983f61187_slices_1-2-3-x.zip
wA5a4e865ca WT 1 46A 5a4e865ca_slices_1-2-3-4.zip
wA5a4e865ca WT 2 87A 5a4e865ca_slices_1-2-3-4.zip
wA5a4e865ca WT 3 24B 5a4e865ca_slices_1-2-3-4.zip
wAd3d31660f WT 1 46A d3d31660f_slices_1-x-2-3.zip
wAd3d31660f WT 2 12B d3d31660f_slices_1-x-2-3.zip
wAd3d31660f WT 3 53B d3d31660f_slices_1-x-2-3.zip
wA41554e619 WT 1 42A 41554e619_slices_x-1-2-3.zip
wA41554e619 WT 2 47B 41554e619_slices_x-1-2-3.zip
wA41554e619 WT 3 53B 41554e619_slices_x-1-2-3.zip
wA6725b26d7 WT 2 61A 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 3 58B 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 4 52B 6725b26d7_slices_1-2-3-4.zip
wAd5b9e0942 WT 1 12A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 2 54A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 3 12B d5b9e0942_slices_1-2-3-x.zip
wAd64812350 WT 1 52A d64812350_slices_x-1-2-3.zip
wAd64812350 WT 2 55B d64812350_slices_x-1-2-3.zip
wAd64812350 WT 3 54B d64812350_slices_x-1-2-3.zip
wAf87e2f168 WT 1 46A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 2 43A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 3 46B f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 4 52B f87e2f168_slices_1-2-3-4.zip
wA8a7fa98bc WT 1 55A 8a7fa98bc_slices_1-2-x-x.zip
wA8a7fa98bc WT 2 41A 8a7fa98bc_slices_1-2-x-x.zip
wAef1f233e7 WT 2 62A ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 3 46B ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 4 52B ef1f233e7_slices_1-2-3-4.zip

Paired Pulse Facilitation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mAd7d9a6cd5 mutant 1 45A d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 3 58B d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 4 41B d7d9a6cd5_slices_1-2-3-4.zip
mA253bc8fc0 mutant 2 61A 253bc8fc0_slices_1-2-x-3.zip
mA253bc8fc0 mutant 3 43B 253bc8fc0_slices_1-2-x-3.zip
mAb5bdcf42c mutant 1 62B b5bdcf42c_slices_x-x-x-1.zip
mA9fa0f988e mutant 1 58A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 2 42A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 3 57B 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 4 53B 9fa0f988e_slices_1-2-3-4.zip
mA40b721c83 mutant 1 86A 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 2 55B 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 3 52B 40b721c83_slices_1-x-2-3.zip
mA40b721c83 mutant 5 61A 40b721c83_slices_4-5-6-7.zip
mA40b721c83 mutant 6 46B 40b721c83_slices_4-5-6-7.zip
mAd9952ae17 mutant 1 15A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 2 41A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 3 15B d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 4 41B d9952ae17_slices_1-2-3-4.zip
mA1b3ebd427 mutant 2 43A 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 3 46B 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 4 52B 1b3ebd427_slices_1-2-3-4.zip
wA6725b26d7 WT 2 61A 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 3 58B 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 4 52B 6725b26d7_slices_1-2-3-4.zip
wAd5b9e0942 WT 1 12A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 2 54A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 3 12B d5b9e0942_slices_1-2-3-x.zip
wAd64812350 WT 1 52A d64812350_slices_x-1-2-3.zip
wAd64812350 WT 2 55B d64812350_slices_x-1-2-3.zip
wAd64812350 WT 3 54B d64812350_slices_x-1-2-3.zip
wAf87e2f168 WT 1 46A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 2 43A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 3 46B f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 4 52B f87e2f168_slices_1-2-3-4.zip
wA8a7fa98bc WT 1 55A 8a7fa98bc_slices_1-2-x-x.zip
wA8a7fa98bc WT 2 41A 8a7fa98bc_slices_1-2-x-x.zip
wAef1f233e7 WT 2 62A ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 3 46B ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 4 52B ef1f233e7_slices_1-2-3-4.zip

Long Term Potentiation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mA48b5fbaeb mutant 1 53A 48b5fbaeb_slices_x-1-2-3.zip
mA48b5fbaeb mutant 2 47B 48b5fbaeb_slices_x-1-2-3.zip
mA48b5fbaeb mutant 3 43B 48b5fbaeb_slices_x-1-2-3.zip
mAdcb8a65dc mutant 1 55A dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 2 44A dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 3 28B dcb8a65dc_slices_1-2-3-4.zip
mAdcb8a65dc mutant 4 61B dcb8a65dc_slices_1-2-3-4.zip
mAc7876080d mutant 1 47A c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 2 53A c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 3 37B c7876080d_slices_1-2-3-4.zip
mAc7876080d mutant 4 44B c7876080d_slices_1-2-3-4.zip
mA1a637500f mutant 1 12A 1a637500f_slices_1-2-3-4.zip
mA1a637500f mutant 3 47B 1a637500f_slices_1-2-3-4.zip
mA1a637500f mutant 4 53B 1a637500f_slices_1-2-3-4.zip
mA786a52f10 mutant 1 37A 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 2 53A 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 3 37B 786a52f10_slices_1-2-3-4.zip
mA786a52f10 mutant 4 44B 786a52f10_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 1 45A d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 3 58B d7d9a6cd5_slices_1-2-3-4.zip
mAd7d9a6cd5 mutant 4 41B d7d9a6cd5_slices_1-2-3-4.zip
mA253bc8fc0 mutant 2 61A 253bc8fc0_slices_1-2-x-3.zip
mA253bc8fc0 mutant 3 43B 253bc8fc0_slices_1-2-x-3.zip
mAb5bdcf42c mutant 1 62B b5bdcf42c_slices_x-x-x-1.zip
mA9fa0f988e mutant 1 58A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 2 42A 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 3 57B 9fa0f988e_slices_1-2-3-4.zip
mA9fa0f988e mutant 4 53B 9fa0f988e_slices_1-2-3-4.zip
mAd9952ae17 mutant 1 15A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 2 41A d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 3 15B d9952ae17_slices_1-2-3-4.zip
mAd9952ae17 mutant 4 41B d9952ae17_slices_1-2-3-4.zip
mA1b3ebd427 mutant 2 43A 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 3 46B 1b3ebd427_slices_1-2-3-4.zip
mA1b3ebd427 mutant 4 52B 1b3ebd427_slices_1-2-3-4.zip
wA68f02fa73 WT 1 38A 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 2 53A 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 3 46B 68f02fa73_slices_1-2-3-4.zip
wA68f02fa73 WT 4 53B 68f02fa73_slices_1-2-3-4.zip
wA983f61187 WT 1 46A 983f61187_slices_1-2-3-x.zip
wA983f61187 WT 2 42A 983f61187_slices_1-2-3-x.zip
wA983f61187 WT 3 57B 983f61187_slices_1-2-3-x.zip
wA5a4e865ca WT 1 46A 5a4e865ca_slices_1-2-3-4.zip
wA5a4e865ca WT 2 87A 5a4e865ca_slices_1-2-3-4.zip
wA5a4e865ca WT 3 24B 5a4e865ca_slices_1-2-3-4.zip
wAd3d31660f WT 1 46A d3d31660f_slices_1-x-2-3.zip
wAd3d31660f WT 2 12B d3d31660f_slices_1-x-2-3.zip
wAd3d31660f WT 3 53B d3d31660f_slices_1-x-2-3.zip
wA41554e619 WT 1 42A 41554e619_slices_x-1-2-3.zip
wA41554e619 WT 2 47B 41554e619_slices_x-1-2-3.zip
wA41554e619 WT 3 53B 41554e619_slices_x-1-2-3.zip
wA6725b26d7 WT 2 61A 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 3 58B 6725b26d7_slices_1-2-3-4.zip
wA6725b26d7 WT 4 52B 6725b26d7_slices_1-2-3-4.zip
wAd5b9e0942 WT 1 12A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 2 54A d5b9e0942_slices_1-2-3-x.zip
wAd5b9e0942 WT 3 12B d5b9e0942_slices_1-2-3-x.zip
wAd64812350 WT 1 52A d64812350_slices_x-1-2-3.zip
wAd64812350 WT 2 55B d64812350_slices_x-1-2-3.zip
wAd64812350 WT 3 54B d64812350_slices_x-1-2-3.zip
wAf87e2f168 WT 1 46A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 2 43A f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 3 46B f87e2f168_slices_1-2-3-4.zip
wAf87e2f168 WT 4 52B f87e2f168_slices_1-2-3-4.zip
wA8a7fa98bc WT 1 55A 8a7fa98bc_slices_1-2-x-x.zip
wA8a7fa98bc WT 2 41A 8a7fa98bc_slices_1-2-x-x.zip
wAef1f233e7 WT 2 62A ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 3 46B ef1f233e7_slices_1-2-3-4.zip
wAef1f233e7 WT 4 52B ef1f233e7_slices_1-2-3-4.zip

Data Files

File NameSizeChecksum (SHA256)
4a6fe1848_slices_1-2-3.zip32692939ab5b1116fd21e8c7e305909913f792b2f258a43e141a03f27a1234569e67ed6a
1b3ebd427_slices_1-2-3-4.zip324747017747230e4d272b063176e93866fea64a414c8b1c5cc0e9b21b325ab7da8801da
f87e2f168_slices_1-2-3-4.zip4647668072850fdec2b862dc595dadb424bf52b4f8d94b9ad74b827cd935665b555f69ef
e8382bc11_slices_1-2-3.zip326298415f45239e7dd0f3eb037a009d195f8a6c44c80574627b45b7102b463770f65b42
983f61187_slices_1-2-3-x.zip516867582534d9ef5b2956eb70a29079b013e1eb8650c297264568b4c99d288acec75b46
c7876080d_slices_1-2-3-4.zip30429559da5fade3f0a82f39bfbe4f21b47d2b10019b50b2ac192901d5352e9c56e7b997
d9952ae17_slices_1-2-3-4.zip393134547fea39eb863268222b13d213e8ff2bc793a49c1f35fc08c3891db3f0345eb1b5
7379e2114_slices_1-2-3.zip29363793034a5d4129e9e6ab233ba7a22cf72414c097fb71227b175965a3379f01d35e97
bad7e5811_slices_1-2-3.zip305003837b0ac5b509cb8e7d1713d5b1a083bf696408f4824e8b744ac909b353c996948d
68f02fa73_slices_1-2-3-4.zip53163903972902adc1ae2f3be3936d877cebf0b5852c22ac46111c45e92865395c862a95
6b79cc872_slices_1-2-3.zip421758925f8946095227d806da47078932e178fa1c81c18070492ab2d1684a1e803c5de5
48b5fbaeb_slices_x-1-2-3.zip29150291f7f624b5a33f530333b89a25f0bd2993a53236b7fcd1ef8a41cb14c1afa9df56
c83faf364_slices_1-2-3.zip28004964d02ca6f702825e342407dceefdaf344f5d53847b7d36e8428120602247231b8e
40b721c83_slices_4-5-6-7.zip2631860117252408141056541f57bda382dd5610f5f3e80ceca4161a61a34fe85e23eab
dcb8a65dc_slices_1-2-3-4.zip38150932ebd27395c9cc8bc81117521d7e6d98c84916a8b2930b6c2d53c5b81523f1980b
b5bdcf42c_slices_x-x-x-1.zip242600710b6dcfa9675f9b12978079b30b33b439677152f98e50874c26dcdff9b0fdef49
9fa0f988e_slices_1-2-3-4.zip36803968d5978d816a439fe547b457a1202fc9a68ed25e750ac2ea9cf1bcef00a8522634
1c1ef6008_slices_1-2-3.zip2949277003ab6214bc6f30a51ea2007970a7e40fc56c3e3b32766df58392745bd6e7f14e
d64812350_slices_x-1-2-3.zip299808433e0a4ab4833ca6d9b947adcd20bd6db38b5ec149bd1d3df1e489068d5b2f0e75
d5b9e0942_slices_1-2-3-x.zip46377442b6a43da7118ef7893acb02f39d0e0a5ef56ca9d658aed557743030f0c615179b
2c0db83c3_slices_x-4-5.zip276024754fac22166207025590489693243f8bcf3c4c60deca996a11aeacbb05f20ad2fa
d3d31660f_slices_1-x-2-3.zip37905989ec17744a008f4143cc4297ec1302d5d57afbb3bb299e2f8e05f2fd2178088bb7
bd6450afb_slices_1-2-3.zip34502810276ce05d0fe050f6cd70227186bb4c40f44d5c0714663dea7e9f409d810c4a5b
786a52f10_slices_1-2-3-4.zip4043073226eb42575bf579f36b2e1afe83b658d9cb34909d4a0467735682b0cc196b06a7
9aaaca937_slices_1-2-3.zip3813558369025150e66e956335b40315723a218d54f8bf20b82a74a84b947b31013ae3a1
1a637500f_slices_1-2-3-4.zip3694842648adbf9c0ae8bd9263bab46b54de8bd8a37f9896d5ec41493eef818f8d42a102
d7d9a6cd5_slices_1-2-3-4.zip3594752769e508e34e0fa16ccc91435298774cc7ca0e3f7a2237c11e69cf96e83f9f0f1c
41554e619_slices_x-1-2-3.zip31664265bd823c04795e2f249953a9542732d3cc55bbe985ac3c6e4bb28f2515eb87f949
2c0db83c3_slices_1-2-3.zip3110360204678ecddb3531d4e5c36030f1f66e182c1f8a78d6be99f20bc79a8c47f77e8d
6725b26d7_slices_1-2-3-4.zip380467378f2129690f5641283d954bb9aa235827a6d457b92aff1856430eafc50be5ed8f
8a7fa98bc_slices_1-2-x-x.zip40700572a1630dee2ba5bcb30aa9f2e7d7fcfe58367399df3fcf776b2ba6e338bbeba16e
253bc8fc0_slices_1-2-x-3.zip37921392c4ffb36f962aa8ae6c7aaea839f94e4ca27b47ea8b0a9df26674790495b71a69
40b721c83_slices_1-x-2-3.zip2566576b00be294af02a21a1d08e03b7bbd4a92a90e7838c8e1b7c9c7ab112766479d1c
5a4e865ca_slices_1-2-3-4.zip33884505747add564ee133e162da23dfc80500129be99d3efd593b50d7cf39ebbc087f33
ef1f233e7_slices_1-2-3-4.zip492193435e52c17e6eda68ce69ae67638716b8ea9bc7bfdd995a20be3af9b384255593ca
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