G2C::Electrophysiology

NR2B-CK2 point mouse

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk  

 

Overview: Effect sizes (Cohen d) for 18 electrophysiology variables

Mutant slices showed little overall electrophysiological difference from wildtype slices, with two of nine variables significantly impacted in these mutants. In the paired pulse facilitation experiment, PPF at 50ms ampl ratio was significantly increased in mutants. In the theta burst stimulation experiment, one electrophysiological variable, burst 1 PPF at 10ms ampl ratio, was significantly increased in mutants. Basal synaptic transmission and long term potentiation experiments were unaffected. Note that in the theta burst analysis, the tenth burst is analysed as representative of individual burst amplitude. Definitions of variables may be found below.

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The G2CMine data warehouse provides slice group summaries and individual mouse observations from the NR2B-CK2 point line phenotyping.

 

Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude. PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio. Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4. LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 26 (9) 2807 (83) 35 (11) 2733 (78) 0.002 ** 0.65
PPF at 50ms, ampl ratio % 26 (9) 164.5 (3.1) 35 (11) 178 (3.3) 0.15 0.023 *
Burst 1, PPF at 10ms, ampl ratio % 26 (9) 152.7 (5.3) 35 (11) 173.9 (5.5) 0.12 0.034 *
Burst 1, EPSP3 depr, ampl ratio % 26 (9) 62.6 (2.2) 35 (11) 60.1 (1.9) 0.79 0.35
Burst 1, ave amplitude µV 26 (9) 1305 (34) 35 (11) 1219 (36) 0.21 0.15
Burst 2, ave amplitude µV 26 (9) 2026 (60) 35 (11) 2026 (70) 0.11 1
Burst 3, ave amplitude µV 26 (9) 2223 (67) 35 (11) 2203 (69) 0.11 0.87
Burst 4, ave amplitude µV 26 (9) 2244 (67) 35 (11) 2228 (68) 0.12 0.89
Burst 5, ave amplitude µV 26 (9) 2212 (65) 35 (11) 2194 (66) 0.12 0.87
Burst 6, ave amplitude µV 26 (9) 2151 (63) 35 (11) 2135 (63) 0.13 0.88
Burst 7, ave amplitude µV 26 (9) 2091 (62) 35 (11) 2071 (62) 0.081 0.85
Burst 8, ave amplitude µV 26 (9) 2042 (62) 35 (11) 2013 (61) 0.089 0.79
Burst 9, ave amplitude µV 26 (9) 1989 (58) 35 (11) 1977 (61) 0.074 0.91
Burst 10, ave amplitude µV 26 (9) 1956 (57) 35 (11) 1926 (60) 0.073 0.78
Burst 2-4 ave amplitude vs Burst 1 % 26 (9) 166.1 (2.9) 35 (11) 179 (4.2) 0.18 0.055
Burst 8-10 ave amplitude vs Burst 2-4 % 26 (9) 92.7 (1) 35 (11) 92.3 (1) 0.11 0.82
LTP vs PTP, amplitude ratio % 26 (9) 80.5 (0.9) 35 (11) 79.8 (1) 0.52 0.63
LTP based on amplitude % 26 (9) 162.2 (6.3) 35 (11) 165.9 (3.7) 0.52 0.59

 

Basal Synaptic Transmission

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Variables shown are: Max fEPSP amplitude, Maximum field excitatory postsynaptic potential (fEPSP) amplitude.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Max fEPSP amplitude µV 26 (9) 2807 (83) 35 (11) 2733 (78) 0.002 ** 0.65

 

Paired Pulse Facilitation

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Variables shown are: PPF at 50ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 50ms, amplitude ratio.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
PPF at 50ms, ampl ratio % 26 (9) 164.5 (3.1) 35 (11) 178 (3.3) 0.15 0.023 *

 

Theta Burst Stimulation

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Variables shown are: Burst 1, PPF at 10ms, ampl ratio, Paired pulse facilitation (PPF), pulses separated by 10ms, amplitude ratio, observed during first two pulses of the first 100Hz burst during theta-burst stimulation. Burst 1, EPSP3 depr, ampl ratio, Depression observed in third fEPSP relative to the second fEPSP of the first 100Hz burst, amplitude ratio. Burst 1, ave amplitude, Average amplitude of four fEPSPs in first burst. Burst 2, ave amplitude, Average amplitude of four fEPSPs in second burst. Burst 3, ave amplitude, Average amplitude of four fEPSPs in third burst. Burst 4, ave amplitude, Average amplitude of four fEPSPs in fourth burst. Burst 5, ave amplitude, Average amplitude of four fEPSPs in fifth burst. Burst 6, ave amplitude, Average amplitude of four fEPSPs in sixth burst. Burst 7, ave amplitude, Average amplitude of four fEPSPs in seventh burst. Burst 8, ave amplitude, Average amplitude of four fEPSPs in eighth burst. Burst 9, ave amplitude, Average amplitude of four fEPSPs in ninth burst. Burst 10, ave amplitude, Average amplitude of four fEPSPs in tenth burst. Burst 2-4 ave amplitude vs Burst 1, Facilitation observed in average amplitude of bursts 2-4, relative to average amplitude of burst 1. Burst 8-10 ave amplitude vs Burst 2-4, Depression observed in average amplitude of bursts 8-10, relative to average amplitude of bursts 2-4.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
Burst 1, PPF at 10ms, ampl ratio % 26 (9) 152.7 (5.3) 35 (11) 173.9 (5.5) 0.12 0.034 *
Burst 1, EPSP3 depr, ampl ratio % 26 (9) 62.6 (2.2) 35 (11) 60.1 (1.9) 0.79 0.35
Burst 1, ave amplitude µV 26 (9) 1305 (34) 35 (11) 1219 (36) 0.21 0.15
Burst 2, ave amplitude µV 26 (9) 2026 (60) 35 (11) 2026 (70) 0.11 1
Burst 3, ave amplitude µV 26 (9) 2223 (67) 35 (11) 2203 (69) 0.11 0.87
Burst 4, ave amplitude µV 26 (9) 2244 (67) 35 (11) 2228 (68) 0.12 0.89
Burst 5, ave amplitude µV 26 (9) 2212 (65) 35 (11) 2194 (66) 0.12 0.87
Burst 6, ave amplitude µV 26 (9) 2151 (63) 35 (11) 2135 (63) 0.13 0.88
Burst 7, ave amplitude µV 26 (9) 2091 (62) 35 (11) 2071 (62) 0.081 0.85
Burst 8, ave amplitude µV 26 (9) 2042 (62) 35 (11) 2013 (61) 0.089 0.79
Burst 9, ave amplitude µV 26 (9) 1989 (58) 35 (11) 1977 (61) 0.074 0.91
Burst 10, ave amplitude µV 26 (9) 1956 (57) 35 (11) 1926 (60) 0.073 0.78
Burst 2-4 ave amplitude vs Burst 1 % 26 (9) 166.1 (2.9) 35 (11) 179 (4.2) 0.18 0.055
Burst 8-10 ave amplitude vs Burst 2-4 % 26 (9) 92.7 (1) 35 (11) 92.3 (1) 0.11 0.82

 

Long Term Potentiation

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Variables shown are: LTP vs PTP, amplitude ratio, Reduction in potentiation from immediately after theta-burst stimulation to one hour later, fEPSP amplitude ratio. LTP based on amplitude, Long term potentiation, ratio of amplitudes of fEPSPs in test pathway and control pathway.

 

Variable Units Wildtype slices (animals) Wildtype mean (SEM) Mutant slices (animals) Mutant mean (SEM) P(animals) P(mutation)
LTP vs PTP, amplitude ratio % 26 (9) 80.5 (0.9) 35 (11) 79.8 (1) 0.52 0.63
LTP based on amplitude % 26 (9) 162.2 (6.3) 35 (11) 165.9 (3.7) 0.52 0.59

Hippocampal brain slices summarised by genotype, followed by a list of the animals from which they were prepared.

View experimental protocols.

 

Hippocampal Slice Electrophysiology Cohort Summary

GenotypeCount
WT9
mutant11

 

Individual Mice

Mouse IDGenotype
wA2bf945d9cWT
wBf40a48a2bWT
wAe3316ba09WT
wAbd9b9f0beWT
wBdc9a0f39eWT
wA1d51eb7e2WT
wBd1e354916WT
wBcde2c2d83WT
wB4e0ad4b12WT
mB1d51eb7e2mutant
mA13ef31c94mutant
mAd1e354916mutant
mAcde2c2d83mutant
mBbd9b9f0bemutant
mAf40a48a2bmutant
mB25e51e0dbmutant
mA4e0ad4b12mutant
mAdc9a0f39emutant
mA25e51e0dbmutant
mB2bf945d9cmutant

Field EPSP (Maximum)

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mAd1e354916 mutant 1 46A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 2 62A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 3 47B d1e354916_slices_1-2-3-x.zip
mB1d51eb7e2 mutant 5 43A 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 6 15B 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 7 84B 1d51eb7e2_slices_4-5-6-7.zip
mA4e0ad4b12 mutant 1 55A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 2 52A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 3 15B 4e0ad4b12_slices_1-2-3-x.zip
mAf40a48a2b mutant 1 12A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 2 53A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 3 46B f40a48a2b_slices_1-2-3-x.zip
mA25e51e0db mutant 1 12A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 2 52A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 3 46B 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 4 12A 25e51e0db_slices_4-5-6-7.zip
mB25e51e0db mutant 5 54A 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 6 12B 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 7 62B 25e51e0db_slices_4-5-6-7.zip
mB2bf945d9c mutant 4 46A 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 6 46B 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 7 52B 2bf945d9c_slices_4-5-6-7.zip
mA13ef31c94 mutant 1 46A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 2 61A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 3 12B 13ef31c94_slices_1-2-3-x.zip
mBbd9b9f0be mutant 4 46A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 5 52A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 6 46B bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 7 52B bd9b9f0be_slices_4-5-6-7.zip
mAcde2c2d83 mutant 1 55A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 2 43A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 3 46B cde2c2d83_slice_1-2-3-x.zip
mAdc9a0f39e mutant 1 46A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 2 52A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 3 46B dc9a0f39e_slice_1-2-3-x.zip
wBd1e354916 WT 4 55A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 5 52A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 6 52B d1e354916_slices_4-5-x-6.zip
wA1d51eb7e2 WT 1 55A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 2 61A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 3 46B 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 4 46A 1d51eb7e2_slices_4-5-6-7.zip
wB4e0ad4b12 WT 4 54A 4e0ad4b12_slices_x-4-5-x.zip
wB4e0ad4b12 WT 5 46B 4e0ad4b12_slices_x-4-5-x.zip
wAe3316ba09 WT 1 46A e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 3 12B e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 4 62A e3316ba09_slices_x-4-5-x.zip
wAe3316ba09 WT 5 12B e3316ba09_slices_x-4-5-x.zip
wBf40a48a2b WT 4 42A f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 5 12B f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 6 41B f40a48a2b_slices_x-4-5-6.zip
wA2bf945d9c WT 1 46A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 2 41A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 3 46B 2bf945d9c_slices_1-2-3-x.zip
wAbd9b9f0be WT 1 12A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 2 52A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 3 46B bd9b9f0be_slices_1-2-3-x.zip
wBcde2c2d83 WT 4 55A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 5 54A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 6 12B cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 7 54B cde2c2d83_slices_4-5-6-7.zip
wBdc9a0f39e WT 4 54A dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 5 58B dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 6 42B dc9a0f39e_slices_x-4-5-6.zip

Paired Pulse Facilitation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mAd1e354916 mutant 1 46A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 2 62A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 3 47B d1e354916_slices_1-2-3-x.zip
mB1d51eb7e2 mutant 5 43A 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 6 15B 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 7 84B 1d51eb7e2_slices_4-5-6-7.zip
mA4e0ad4b12 mutant 1 55A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 2 52A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 3 15B 4e0ad4b12_slices_1-2-3-x.zip
mAf40a48a2b mutant 1 12A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 2 53A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 3 46B f40a48a2b_slices_1-2-3-x.zip
mA25e51e0db mutant 1 12A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 2 52A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 3 46B 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 4 12A 25e51e0db_slices_4-5-6-7.zip
mB25e51e0db mutant 5 54A 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 6 12B 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 7 62B 25e51e0db_slices_4-5-6-7.zip
mB2bf945d9c mutant 4 46A 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 6 46B 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 7 52B 2bf945d9c_slices_4-5-6-7.zip
mA13ef31c94 mutant 1 46A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 2 61A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 3 12B 13ef31c94_slices_1-2-3-x.zip
mBbd9b9f0be mutant 4 46A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 5 52A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 6 46B bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 7 52B bd9b9f0be_slices_4-5-6-7.zip
mAcde2c2d83 mutant 1 55A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 2 43A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 3 46B cde2c2d83_slice_1-2-3-x.zip
mAdc9a0f39e mutant 1 46A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 2 52A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 3 46B dc9a0f39e_slice_1-2-3-x.zip
wBd1e354916 WT 4 55A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 5 52A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 6 52B d1e354916_slices_4-5-x-6.zip
wA1d51eb7e2 WT 1 55A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 2 61A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 3 46B 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 4 46A 1d51eb7e2_slices_4-5-6-7.zip
wB4e0ad4b12 WT 4 54A 4e0ad4b12_slices_x-4-5-x.zip
wB4e0ad4b12 WT 5 46B 4e0ad4b12_slices_x-4-5-x.zip
wAe3316ba09 WT 1 46A e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 3 12B e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 4 62A e3316ba09_slices_x-4-5-x.zip
wAe3316ba09 WT 5 12B e3316ba09_slices_x-4-5-x.zip
wBf40a48a2b WT 4 42A f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 5 12B f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 6 41B f40a48a2b_slices_x-4-5-6.zip
wA2bf945d9c WT 1 46A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 2 41A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 3 46B 2bf945d9c_slices_1-2-3-x.zip
wAbd9b9f0be WT 1 12A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 2 52A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 3 46B bd9b9f0be_slices_1-2-3-x.zip
wBcde2c2d83 WT 4 55A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 5 54A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 6 12B cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 7 54B cde2c2d83_slices_4-5-6-7.zip
wBdc9a0f39e WT 4 54A dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 5 58B dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 6 42B dc9a0f39e_slices_x-4-5-6.zip

Long Term Potentiation

Mouse IDGenotypeSlice NumberRecording ChannelFile Name
mAd1e354916 mutant 1 46A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 2 62A d1e354916_slices_1-2-3-x.zip
mAd1e354916 mutant 3 47B d1e354916_slices_1-2-3-x.zip
mB1d51eb7e2 mutant 5 43A 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 6 15B 1d51eb7e2_slices_4-5-6-7.zip
mB1d51eb7e2 mutant 7 84B 1d51eb7e2_slices_4-5-6-7.zip
mA4e0ad4b12 mutant 1 55A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 2 52A 4e0ad4b12_slices_1-2-3-x.zip
mA4e0ad4b12 mutant 3 15B 4e0ad4b12_slices_1-2-3-x.zip
mAf40a48a2b mutant 1 12A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 2 53A f40a48a2b_slices_1-2-3-x.zip
mAf40a48a2b mutant 3 46B f40a48a2b_slices_1-2-3-x.zip
mA25e51e0db mutant 1 12A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 2 52A 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 3 46B 25e51e0db_slices_1-2-3-x.zip
mA25e51e0db mutant 4 12A 25e51e0db_slices_4-5-6-7.zip
mB25e51e0db mutant 5 54A 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 6 12B 25e51e0db_slices_4-5-6-7.zip
mA25e51e0db mutant 7 62B 25e51e0db_slices_4-5-6-7.zip
mB2bf945d9c mutant 4 46A 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 6 46B 2bf945d9c_slices_4-5-6-7.zip
mB2bf945d9c mutant 7 52B 2bf945d9c_slices_4-5-6-7.zip
mA13ef31c94 mutant 1 46A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 2 61A 13ef31c94_slices_1-2-3-x.zip
mA13ef31c94 mutant 3 12B 13ef31c94_slices_1-2-3-x.zip
mBbd9b9f0be mutant 4 46A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 5 52A bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 6 46B bd9b9f0be_slices_4-5-6-7.zip
mBbd9b9f0be mutant 7 52B bd9b9f0be_slices_4-5-6-7.zip
mAcde2c2d83 mutant 1 55A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 2 43A cde2c2d83_slice_1-2-3-x.zip
mAcde2c2d83 mutant 3 46B cde2c2d83_slice_1-2-3-x.zip
mAdc9a0f39e mutant 1 46A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 2 52A dc9a0f39e_slice_1-2-3-x.zip
mAdc9a0f39e mutant 3 46B dc9a0f39e_slice_1-2-3-x.zip
wBd1e354916 WT 4 55A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 5 52A d1e354916_slices_4-5-x-6.zip
wBd1e354916 WT 6 52B d1e354916_slices_4-5-x-6.zip
wA1d51eb7e2 WT 1 55A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 2 61A 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 3 46B 1d51eb7e2_slices_1-2-3-x.zip
wA1d51eb7e2 WT 4 46A 1d51eb7e2_slices_4-5-6-7.zip
wB4e0ad4b12 WT 4 54A 4e0ad4b12_slices_x-4-5-x.zip
wB4e0ad4b12 WT 5 46B 4e0ad4b12_slices_x-4-5-x.zip
wAe3316ba09 WT 1 46A e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 3 12B e3316ba09_slices_1-2-3-x.zip
wAe3316ba09 WT 4 62A e3316ba09_slices_x-4-5-x.zip
wAe3316ba09 WT 5 12B e3316ba09_slices_x-4-5-x.zip
wBf40a48a2b WT 4 42A f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 5 12B f40a48a2b_slices_x-4-5-6.zip
wBf40a48a2b WT 6 41B f40a48a2b_slices_x-4-5-6.zip
wA2bf945d9c WT 1 46A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 2 41A 2bf945d9c_slices_1-2-3-x.zip
wA2bf945d9c WT 3 46B 2bf945d9c_slices_1-2-3-x.zip
wAbd9b9f0be WT 1 12A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 2 52A bd9b9f0be_slices_1-2-3-x.zip
wAbd9b9f0be WT 3 46B bd9b9f0be_slices_1-2-3-x.zip
wBcde2c2d83 WT 4 55A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 5 54A cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 6 12B cde2c2d83_slices_4-5-6-7.zip
wBcde2c2d83 WT 7 54B cde2c2d83_slices_4-5-6-7.zip
wBdc9a0f39e WT 4 54A dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 5 58B dc9a0f39e_slices_x-4-5-6.zip
wBdc9a0f39e WT 6 42B dc9a0f39e_slices_x-4-5-6.zip

Data Files

File NameSizeChecksum (SHA256)
1d51eb7e2_slices_4-5-6-7.zip4428534387eee309cc1310bde22de4dfa18b80470338e8e0affee24767d3722f302c178e
4e0ad4b12_slices_1-2-3-x.zip358977133e8f2f13cb4d267072bfafcc19af6ef42837c00de59e6f010eed6bcc9cfd9b9c
e3316ba09_slices_x-4-5-x.zip453238905dc846ae57dbc4502b9644795c48e4bb04ef9cdbf7dd4b10af77b8c878ae425f
d1e354916_slices_4-5-x-6.zip54887340f93d33d4760897f51847470f068850f5234f27aaed5e6cb7a9161a2b0c5ed13d
2bf945d9c_slices_4-5-6-7.zip55521437f159318ffd3a4eb1b315813695b96f46b8be0a181b3715d9a341f18c262a3604
4e0ad4b12_slices_x-4-5-x.zip402312526e899e990a6987ff394ca38bd9f3e61d94bc41adcdb60ff0dfb303ad7d917de7
e3316ba09_slices_1-2-3-x.zip32493717c48ffb8ca2d05ceaa60160e1028fe74573582a59c08e8810003fd4771cbbff9a
25e51e0db_slices_4-5-6-7.zip41453344420eeec90ec7ef813b683a3b280cb62a7ea7626b1269e7eb838045025c9c8dbb
dc9a0f39e_slice_1-2-3-x.zip42774410fcc799f3c00664ec817bcc9de5c20876491e267ae2d3e2a2de05503aae60004b
d1e354916_slices_1-2-3-x.zip3246507319d3a3bcbc9af2e37591402c87661428241bb2269cc84faeda31e33c1dd11c09
13ef31c94_slices_1-2-3-x.zip28809932fd4d6f2c6be004e251bd6442d06c4019649d327695f5750857e75ff411ddd2ad
cde2c2d83_slices_4-5-6-7.zip70650190b906ba9cd82bcc07748666950e9bb5cfb65b2f490a73c9dfb217d30cc6b59fd3
25e51e0db_slices_1-2-3-x.zip32650526c96eb7578149f4844f5ba513e73073873dea66d963e7bf6f574ee34c15b2899c
2bf945d9c_slices_1-2-3-x.zip40183661410edf7a1eaaee6563acd9dfa6421ebd7edc921507cae52338e1198947d0df66
bd9b9f0be_slices_1-2-3-x.zip31802906709d135c2c954b831bd0679565ef9144eadaaaa2d69125bd23679cba6c930254
1d51eb7e2_slices_1-2-3-x.zip30636620c4789065673ab05bb0999cd974272880ac689f0bbd2e92b9acc435b6086d891f
f40a48a2b_slices_x-4-5-6.zip445678216b635cafae6bf210270cfa985f96ffb1cecf6106176ad835439f92365e479578
f40a48a2b_slices_1-2-3-x.zip28741800cfeb5bd569a21fc21387342d77417a6f7b38cd9380349dbf624a5d14cc876c87
dc9a0f39e_slices_x-4-5-6.zip48878742632470ccaa1d831f09716b2fc17cb15d8c71e428375e8982ae4cb888f2b07f89
cde2c2d83_slice_1-2-3-x.zip3324896932e82cb81b18f33791bb7ff8e1c24ff5c63b79631c43cbace92463c94e95c047
bd9b9f0be_slices_4-5-6-7.zip41172932b47665703cefbae6aeaf85d3c56a026b11c79f70792331058bf08158a5639569
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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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