G2Cdb::Allele report

Mutation type

Altered genes (1)

Gene Symbol Species Description
G00000030 NOS1 Homo sapiens nitric oxide synthase 1 (neuronal)

Diseases (1)

Disease Description Nervous effect
D00000193 Alzheimer's disease Y

Literature (1)

Pubmed - human_disease

  • No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer Disease.

    Liou YJ, Hong CJ, Liu HC, Liu CY, Liu TY, Chen IC and Tsai SJ

    Section of Psychiatry, Yu-Li Veterans Hospital, Hualien, Taiwan, Republic of China.

    Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.

    American journal of medical genetics 2002;114;6;687-8

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EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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