G2Cdb::Gene report

Gene id
G00000030
Gene symbol
NOS1 (HGNC)
Species
Homo sapiens
Description
nitric oxide synthase 1 (neuronal)
Orthologue
G00000005 (Mus musculus)

Databases (8)

Gene
ENSG00000089250 (Ensembl human gene)
4842 (Entrez Gene)
76 (G2Cdb plasticity & disease)
NOS1 (GeneCards)
Literature
163731 (OMIM)
Marker Symbol
HGNC:7872 (HGNC)
Protein Expression
2167 (human protein atlas)
Protein Sequence
P29475 (UniProt)

Synonyms (1)

  • nNOS

Diseases (16)

Disease Nervous effect Mutations Found Literature Mutations Type Genetic association?
D00000289: Infantile pyloric stenosis N Y (8571963) Unknown (?) Y
D00000231: Essential hypertension N Y (9298742) Repeat polymorphism (RP) N
D00000240: Asthma N Y (10641565) Unknown (?) Y
D00000240: Asthma N Y (10673365) Microsatellite variation (MSV) Y
D00000240: Asthma N Y (10833424) Dinucleotide polymorphism (DNP) Y
D00000270: End-stage renal disease N Y (11071967) Microsatellite variation (MSV) ?
D00000240: Asthma N Y (11112111) Dinucleotide polymorphism (DNP) Y
D00000240: Asthma N Y (11668616) Single nucleotide polymorphism (SNP) Y
D00000191: Parkinson's disease Y Y (11809160) Dinucleotide polymorphism (DNP) Y
D00000166: Schizophrenia Y Y (12140778) Single nucleotide polymorphism (SNP) Y
D00000193: Alzheimer's disease Y Y (12210288) Dinucleotide polymorphism (DNP) N
D00000191: Parkinson's disease Y Y (12490535) Dinucleotide polymorphism (DNP) Y
D00000276: Preeclampsia N Y (12699878) Microinsertion (MI) N
D00000171: Major depressive disorder Y Y (12759556) Single nucleotide polymorphism (SNP) N
D00000166: Schizophrenia Y Y (14623375) Repeat polymorphism (RP) N
D00000170: Bipolar disorder Y Y (14681919) Single nucleotide polymorphism (SNP) N
D00000195: Multiple sclerosis Y Y (14759629) Microsatellite polymorphism (MSP) N
D00000156: Cystic fibrosis N Y (14760158) Repeat polymorphism (RP) Y
D00000316: Immunoglobulin E-mediated allergic diseases N Y (15080837) Single nucleotide polymorphism (SNP) ?
D00000204: Migraine Y Y (16191396) Microsatellite repeat polymorphism (MSRP) N
D00000242: Achalasia N Y (16848803) Microsatellite repeat polymorphism (MSRP) N
D00000242: Achalasia N Y (16848803) Restriction fragment length polymorphism (RFLP) N
D00000181: Primary nocturnal enuresis N Y (17365914) Single nucleotide polymorphism (SNP) Y

References

Literature (215)

Pubmed - human_disease

Pubmed - other

OMIM - other

Gene lists (6)

Gene List Source Species Name Description Gene count
L00000009 G2C Homo sapiens Human PSD Human orthologues of mouse PSD adapted from Collins et al (2006) 1080
L00000015 G2C Homo sapiens Human NRC Human orthologues of mouse NRC adapted from Collins et al (2006) 186
L00000016 G2C Homo sapiens Human PSP Human orthologues of mouse PSP adapted from Collins et al (2006) 1121
L00000032 G2C Homo sapiens Pocklington H1 Human orthologues of cluster 1 (mouse) from Pocklington et al (2006) 21
L00000061 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-CONSENSUS Mouse cortex PSD consensus (ortho) 984
L00000071 G2C Homo sapiens BAYES-COLLINS-MOUSE-PSD-FULL Mouse cortex PSD full list (ortho) 1556
© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

Cookies Policy | Terms and Conditions. This site is hosted by Edinburgh University and the Genes to Cognition Programme.