G2Cdb::Gene report

Gene id: G00000030
Gene symbol: NOS1 (HGNC)
Species: Homo sapiens
Description: nitric oxide synthase 1 (neuronal)
Orthologue: G00000005 (Mus musculus)

Databases (8)
Synonyms (1)
Diseases (16)
Literature (215)
Gene lists (6)

Databases (8)

Gene: ENSG00000089250 (Ensembl human gene); 4842 (Entrez Gene); 76 (G2Cdb plasticity & disease); NOS1 (GeneCards)
Literature: 163731 (OMIM)
Marker Symbol: HGNC:7872 (HGNC)
Protein Expression: 2167 (human protein atlas)
Protein Sequence: P29475 (UniProt)

Synonyms (1)

nNOS

Diseases (16)

Disease	Nervous effect	Mutations Found	Literature	Mutations Type	Genetic association?
D00000289: Infantile pyloric stenosis	N	Y	(8571963)	Unknown (?)	Y
D00000231: Essential hypertension	N	Y	(9298742)	Repeat polymorphism (RP)	N
D00000240: Asthma	N	Y	(10641565)	Unknown (?)	Y
D00000240: Asthma	N	Y	(10673365)	Microsatellite variation (MSV)	Y
D00000240: Asthma	N	Y	(10833424)	Dinucleotide polymorphism (DNP)	Y
D00000270: End-stage renal disease	N	Y	(11071967)	Microsatellite variation (MSV)	?
D00000240: Asthma	N	Y	(11112111)	Dinucleotide polymorphism (DNP)	Y
D00000240: Asthma	N	Y	(11668616)	Single nucleotide polymorphism (SNP)	Y
D00000191: Parkinson's disease	Y	Y	(11809160)	Dinucleotide polymorphism (DNP)	Y
D00000166: Schizophrenia	Y	Y	(12140778)	Single nucleotide polymorphism (SNP)	Y
D00000193: Alzheimer's disease	Y	Y	(12210288)	Dinucleotide polymorphism (DNP)	N
D00000191: Parkinson's disease	Y	Y	(12490535)	Dinucleotide polymorphism (DNP)	Y
D00000276: Preeclampsia	N	Y	(12699878)	Microinsertion (MI)	N
D00000171: Major depressive disorder	Y	Y	(12759556)	Single nucleotide polymorphism (SNP)	N
D00000166: Schizophrenia	Y	Y	(14623375)	Repeat polymorphism (RP)	N
D00000170: Bipolar disorder	Y	Y	(14681919)	Single nucleotide polymorphism (SNP)	N
D00000195: Multiple sclerosis	Y	Y	(14759629)	Microsatellite polymorphism (MSP)	N
D00000156: Cystic fibrosis	N	Y	(14760158)	Repeat polymorphism (RP)	Y
D00000316: Immunoglobulin E-mediated allergic diseases	N	Y	(15080837)	Single nucleotide polymorphism (SNP)	?
D00000204: Migraine	Y	Y	(16191396)	Microsatellite repeat polymorphism (MSRP)	N
D00000242: Achalasia	N	Y	(16848803)	Microsatellite repeat polymorphism (MSRP)	N
D00000242: Achalasia	N	Y	(16848803)	Restriction fragment length polymorphism (RFLP)	N
D00000181: Primary nocturnal enuresis	N	Y	(17365914)	Single nucleotide polymorphism (SNP)	Y

References

Literature (215)

Pubmed - human_disease

Pubmed - other

OMIM - other

608226

Gene lists (6)

Gene List	Source	Species	Name	Description	Gene count
L00000009	G2C	Homo sapiens	Human PSD	Human orthologues of mouse PSD adapted from Collins et al (2006)	1080
L00000015	G2C	Homo sapiens	Human NRC	Human orthologues of mouse NRC adapted from Collins et al (2006)	186
L00000016	G2C	Homo sapiens	Human PSP	Human orthologues of mouse PSP adapted from Collins et al (2006)	1121
L00000032	G2C	Homo sapiens	Pocklington H1	Human orthologues of cluster 1 (mouse) from Pocklington et al (2006)	21
L00000061	G2C	Homo sapiens	BAYES-COLLINS-MOUSE-PSD-CONSENSUS	Mouse cortex PSD consensus (ortho)	984
L00000071	G2C	Homo sapiens	BAYES-COLLINS-MOUSE-PSD-FULL	Mouse cortex PSD full list (ortho)	1556