G2Cdb::Gene report

Gene id: G00001807
Gene symbol: MBP (HGNC)
Species: Homo sapiens
Description: myelin basic protein
Orthologue: G00000558 (Mus musculus)

Databases (8)
Diseases (6)
Literature (129)
Gene lists (10)

Databases (8)

Gene: ENSG00000197971 (Ensembl human gene); 4155 (Entrez Gene); 102 (G2Cdb plasticity & disease); MBP (GeneCards)
Literature: 159430 (OMIM)
Marker Symbol: HGNC:6925 (HGNC)
Protein Expression: 2300 (human protein atlas)
Protein Sequence: P02686 (UniProt)

Diseases (6)

Disease	Nervous effect	Mutations Found	Literature	Mutations Type	Genetic association?
D00000195: Multiple sclerosis	Y	Y	(1383661)	Unknown (?)	Y
D00000317: 18q-syndrome	Y	Y	(1383862)	Deletion (D)	Y
D00000195: Multiple sclerosis	Y	Y	(1691612)	Restriction fragment length polymorphism (RFLP)	Y
D00000317: 18q-syndrome	Y	Y	(1700607)	Deletion (D)	Y
D00000195: Multiple sclerosis	Y	Y	(7515903)	Repeat polymorphism (RP)	N
D00000195: Multiple sclerosis	Y	Y	(7523603)	Amplification fragment length polymorphism (AmpFLP)	N
D00000195: Multiple sclerosis	Y	Y	(7530769)	Unknown (?)	N
D00000195: Multiple sclerosis	Y	Y	(7561955)	Unknown (?)	Y
D00000195: Multiple sclerosis	Y	Y	(7685461)	Microsatellite variation (MSV)	N
D00000170: Bipolar disorder	Y	Y	(8723042)	Translocation (T)	N
D00000169: Schizoaffective disorder	Y	Y	(8723042)	Translocation (T)	N
D00000317: 18q-syndrome	Y	Y	(8728701)	Deletion (D)	N
D00000195: Multiple sclerosis	Y	Y	(8739431)	Repeat polymorphism (RP)	Y
D00000317: 18q-syndrome	Y	Y	(8767586)	Deletion (D)	Y
D00000317: 18q-syndrome	Y	Y	(8933867)	Deletion (D)	?
D00000317: 18q-syndrome	Y	Y	(9259379)	Deletion (D)	Y
D00000195: Multiple sclerosis	Y	Y	(9345452)	Repeat polymorphism (RP)	N
D00000226: Monosymptomatic idiopathic optic neuritis	Y	Y	(9345452)	Repeat polymorphism (RP)	N
D00000195: Multiple sclerosis	Y	Y	(9460711)	Single nucleotide polymorphism (SNP)	N
D00000195: Multiple sclerosis	Y	Y	(9482678)	Repeat polymorphism (RP)	N
D00000195: Multiple sclerosis	Y	Y	(10871781)	Deletion (D)	Y
D00000195: Multiple sclerosis	Y	Y	(10871781)	Polymorphism (P)	Y
D00000195: Multiple sclerosis	Y	Y	(12939427)	Repeat polymorphism (RP)	Y
D00000317: 18q-syndrome	Y	Y	(14508777)	Deletion (D)	Y
D00000199: Epilepsy (intractable)	Y	Y	(14631750)	Deletion (D)	Y

References

Literature (129)

Pubmed - human_disease

Pubmed - other

OMIM - other

605601

Gene lists (10)

Gene List	Source	Species	Name	Description	Gene count
L00000009	G2C	Homo sapiens	Human PSD	Human orthologues of mouse PSD adapted from Collins et al (2006)	1080
L00000011	G2C	Homo sapiens	Human clathrin	Human orthologues of mouse clathrin coated vesicle genes adapted from Collins et al (2006)	150
L00000012	G2C	Homo sapiens	Human Synaptosome	Human orthologues of mouse synaptosome adapted from Collins et al (2006)	152
L00000015	G2C	Homo sapiens	Human NRC	Human orthologues of mouse NRC adapted from Collins et al (2006)	186
L00000016	G2C	Homo sapiens	Human PSP	Human orthologues of mouse PSP adapted from Collins et al (2006)	1121
L00000032	G2C	Homo sapiens	Pocklington H1	Human orthologues of cluster 1 (mouse) from Pocklington et al (2006)	21
L00000059	G2C	Homo sapiens	BAYES-COLLINS-HUMAN-PSD-CONSENSUS	Human cortex PSD consensus	748
L00000061	G2C	Homo sapiens	BAYES-COLLINS-MOUSE-PSD-CONSENSUS	Mouse cortex PSD consensus (ortho)	984
L00000069	G2C	Homo sapiens	BAYES-COLLINS-HUMAN-PSD-FULL	Human cortex biopsy PSD full list	1461
L00000071	G2C	Homo sapiens	BAYES-COLLINS-MOUSE-PSD-FULL	Mouse cortex PSD full list (ortho)	1556