G2Cdb::Gene report

Gene id
G00002162
Gene symbol
FUS (HGNC)
Species
Homo sapiens
Description
fused in sarcoma
Orthologue
G00000913 (Mus musculus)

Databases (8)

Curated Gene
OTTHUMG00000132395 (Vega human gene)
Gene
ENSG00000089280 (Ensembl human gene)
2521 (Entrez Gene)
67 (G2Cdb plasticity & disease)
FUS (GeneCards)
Literature
137070 (OMIM)
Marker Symbol
HGNC:4010 (HGNC)
Protein Sequence
P35637 (UniProt)

Synonyms (3)

  • FUS1
  • TLS
  • hnRNP-P2

Diseases (13)

Disease Nervous effect Mutations Found Literature Mutations Type Genetic association?
D00000009: Myxoid liposarcoma N Y (7485386) Translocation fusion (with another gene) (TF) Y
D00000041: Round cell liposarcoma N Y (7485386) Translocation fusion (with another gene) (TF) Y
D00000007: Malignant liposarcoma N Y (7503811) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (7533529) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (7566973) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (7566973) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (7805034) Translocation fusion (with another gene) (TF) Y
D00000041: Round cell liposarcoma N Y (7805034) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (7987849) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (8523819) Translocation fusion (with another gene) (TF) Y
D00000006: Malignant fibrous histiocytoma N Y (8523819) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (9242552) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (9315104) Translocation fusion (with another gene) (TF) Y
D00000093: Acute myeloid leukaemia N Y (9315104) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (9676855) Translocation fusion (with another gene) (TF) Y
D00000041: Round cell liposarcoma N Y (9676855) Translocation fusion (with another gene) (TF) Y
D00000039: Liposarcoma (well-differentiated) N Y (9676855) Translocation fusion (with another gene) (TF) Y
D00000037: Pleomorphic liposarcoma N Y (9676855) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (10347549) Translocation fusion (with another gene) (TF) Y
D00000104: Angiomatoid fibrous histiocytoma N Y (11063972) Translocation fusion (with another gene) (TF) Y
D00000009: Myxoid liposarcoma N Y (11162437) Translocation fusion (with another gene) (TF) Y
D00000010: Myxoid well-differentiated liposarcoma N Y (11229517) Translocation fusion (with another gene) (TF) N
D00000005: Low grade fibromyxoid sarcoma N Y (12915480) Translocation fusion (with another gene) (TF) Y
D00000005: Low grade fibromyxoid sarcoma N Y (15139001) Translocation fusion (with another gene) (TF) Y
D00000005: Low grade fibromyxoid sarcoma N Y (15640831) Translocation fusion (with another gene) (TF) Y
D00000037: Pleomorphic liposarcoma N Y (15720420) Translocation fusion (with another gene) (TF) Y
D00000087: Acute lymphoblastic leukaemia N Y (16263589) Translocation fusion (with another gene) (TF) Y
D00000005: Low grade fibromyxoid sarcoma N Y (16287497) Translocation fusion (with another gene) (TF) N
D00000093: Acute myeloid leukaemia N Y (16303180) Translocation fusion (with another gene) (TF) Y
D00000013: Myxoid oral liposarcoma N Y (16414544) Translocation fusion (with another gene) (TF) Y
D00000101: Paediatric acute myelocytic leukaemia N Y (16737920) Translocation fusion (with another gene) (TF) Y
D00000005: Low grade fibromyxoid sarcoma N Y (16931951) Translocation fusion (with another gene) (TF) Y

References

Literature (91)

Pubmed - human_disease

Pubmed - other

Gene lists (2)

Gene List Source Species Name Description Gene count
L00000015 G2C Homo sapiens Human NRC Human orthologues of mouse NRC adapted from Collins et al (2006) 186
L00000016 G2C Homo sapiens Human PSP Human orthologues of mouse PSP adapted from Collins et al (2006) 1121
© G2C 2014. The Genes to Cognition Programme received funding from The Wellcome Trust and the EU FP7 Framework Programmes:
EUROSPIN (FP7-HEALTH-241498), SynSys (FP7-HEALTH-242167) and GENCODYS (FP7-HEALTH-241995).

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