Genes to Cognition Programme

Mouse lines phenotyped in the G2C Programme

S.G.N. Grant and the G2C Consortium

Corresponding email: Seth.Grant@ed.ac.uk

Schematic diagram of postsynaptic proteins mutated in this study. Lines show known protein-protein interactions. Key, major protein classes.

Genes to Cognition datasets

Dataset	Type	View
Mouse behaviour - acquired (raw) data	Primary data	View
Mouse behaviour - complete analysis	Statistical analysis	View
Hippocampal brain slice electrophysiology - acquired (raw) data	Primary data	View
Hippocampal brain slice electrophysiology - complete analysis	Statistical analysis	View
Hippocampal Transcriptome Differential Expression Analysis - microarray data	Microarray data	View
G2CMine - phenotypic data integration and intelligent querying	Data warehouse	View

Individual G2C mouse lines

Mouse Line	Behaviour	Electrophysiology	G2CMine
14-3-3 θ knock-out mouse	View	No	View
Akap9 knock-out mouse	View	View	View
Akt2 knock-out mouse	View	View	View
alpha-CaMKII knock-out mouse	View	View	View
beta-Pix knock-out mouse	No	View	View
CINAP knock-out mouse	View	View	View
CITRON knock-out mouse	No	View	View
Cortactin knock-out mouse	View	View	View
CRIPT knock-out mouse	View	No	View
CYFIP1 knock-out mouse	View	View	View
CYFIP1 knock-out mouse	No	View	View
CYPIN knock-out mouse	View	View	View
Dasm1 knock-out mouse	View	View	View
Dip1/2-E9 knock-out mouse	View	View	View
Drebrin knock-out mouse	No	View	View
Dusp4 knock-out mouse	View	View	View
Dusp6 knock-out mouse	View	View	View
Dusp6 knock-out mouse	View	No	View
Dusp7 knock-out mouse	View	View	View
Git1 knock-out mouse	View	View	View
GKAP knock-out mouse	View	View	View
GKAP2 knock-out mouse	View	View	View
GKAP4 knock-out mouse	View	View	View
Glu1 knock-out mouse	View	View	View
GluR1 knock-out mouse	View	View	View
Gnb1 knock-out mouse	View	View	View
GRIT knock-out mouse	View	View	View
H-Ras knock-out mouse	View	View	View
Iqsec1 knock-out mouse	View	View	View
Iqsec3 knock-out mouse	View	View	View
IRSp53 knock-out mouse	View	View	View
Kras knock-out mouse	View	View	View
MAGUIN-1 knock-out mouse	View	View	View
MUPP1 knock-out mouse	View	View	View
nArgBP2 knock-out mouse	View	View	View
NF1 knock-out mouse	View	View	View
nGAP knock-out mouse	View	View	View
NR2A-2BCTR knock-in mouse	No	View	View
NR2A-dC truncation mouse	View	View	View
NR2A-dC/NR2B-dV mouse	No	View	View
NR2B-2ACTR knock-in mouse	View	View	View
NR2B-CK2 point mouse	View	View	View
NR2B-dC truncation mouse	View	View	View
NR2B-dV point mouse	View	View	View
nRapGEP knock-out mouse	View	View	View
NSF knock-out mouse	View	View	View
PIKE knock-out mouse	View	View	View
Prr7 knock-out mouse	View	View	View
PSD-93 knock-out mouse	View	View	View
PSD-93/S-SCAM knock-out mouse	View	No	View
PSD-95-GK truncation mouse	View	View	View
PSD-95-PDZ3 knock-out mouse	View	View	View
PSD-95-PDZ3 knock-out mouse	View	View	View
PSD-95-SH3 point mouse	View	View	View
Rap1gap knock-out mouse	View	No	View
Rassf1 knock-out mouse	View	View	View
S-SCAM knock-out mouse	View	View	View
SAP102 knock-out mouse	View	No	View
SAP102 knock-out mouse	View	View	View
SAP97 knock-out mouse	View	View	View
SHANK2 knock-out mouse	View	View	View
SPAR knock-out mouse	View	View	View
SynCam knock-out mouse	View	View	View
SynGAP knock-out mouse	View	View	View
Tanc1 knock-out mouse	No	View	View
TNiK knock-out mouse	View	View	View
ZO-1 knock-out mouse	View	View	View